Bed bug sprays usually act as an insecticide and repellent. The best kind of bed bug sprays should kill bed bugs on contact and need to be used repeatedly to help eliminate your bug problem. According to the Texas A&M University, bed bug sprays are best used in combination with other bug control methods like natural bed bug powders. This is because bed bugs don’t build up resistance to natural bug powders and products like diatomaceous earth which kills bed bugs as long as the powder is dry.5
Insect bites, including those from the bedbug, have been proposed as a factor contributing to the formation of a cutaneous reaction termed papular urticaria. Patients with papular urticaria have been shown to demonstrate immunoglobulin (Ig) G antibodies to bedbug (C lectularius) antigens. [10] Thus, IgG against C lectularius, Cimex pipiens, and Pulex irritans in patients with papular urticaria may contribute the pathogenesis of this condition.
Prepare the room by separating treated from untreated furniture.  This will involve moving all your furniture to one side of the infested room (Remember, you’ve already assessed which rooms you think are infested.  You may not need to do this in every room).  The process is important because if you treat half of the items in a room and leave other areas untreated, bed bugs may return to the previously treated areas from untreated sites. Take all clothes from drawers, infested closets, etc. and double bag them in clear plastic bags (clear bags are easier to see where things are). Also double bag all personal items (toys, papers, books, electronics, CDs, or anything that could serve as a hiding place for bed bugs) and set them aside until they can be carefully treated, cleaned or inspected. 
Bedbugs are highly resistant to many sprays. There are, however, certain sprays that may be able to kill bedbugs. Check with a professional exterminator about advice using sprays to try and remove the bedbugs yourself. Dead bedbugs usually won't move, may be arched back, or red in color. Ultimately, you may be better off replacing your mattress and bedding and fumigating your home to kill the bedbugs.
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First off you should ALWAYS go to pest control if you think you have bedbugs! You shouldn’t try and get rid of them yourself, 99% of the time it does not work. Plus even if you removed infected areas and wash them it wouldn’t kill the eggs. Plus bedbugs are very easy to get but very hard to get rid of. So you should never do it yourself it won’t work!
You can make a natural bed bug bite treatment by putting 1 cup distilled water in a spray bottle and adding 10-15 drops tea tree oil. Shake well and spray on areas of skin that have clusters of bed bug bites. Or, you could spray the remedy on a cotton pad and apply to the itchy bumps on your skin. You can also dilutes tea tree oil with a carrier oil, such as coconut oil or sweet almond oil (a few drops of tea tree per one tablespoon of carrier oil).
Pay attention to when the bites occur. Consider, for example, if you notice the bites after waking up when previously you hadn't noticed them. However, this can also be difficult to determine because each person's reaction time can vary significantly. Symptoms that result from the bite can manifest at any point from a couple of hours to more than a week after the bite occurred.
Bedbug infestations seem to be increasing around the world at an alarming rate, possibly due to insecticide resistance. [1] Resistance to pyrethroid insecticides is already widespread in the United States. The bedbug occurs in aggregations when conditions are favorable, but the arthropods disperse when conditions are unfavorable. [2] Active female dispersal can potentially lead to treatment failures and should be taken into account when using control methods.

Bedbugs lurk in cracks and crevices and they've been living on human blood for centuries. Though they aren't known to transmit disease or pose any serious medical risk, the stubborn parasites can leave itchy and unsightly bites. However, bedbugs don't always leave marks. The best way to tell if you have a bedbug infestation is to see the live, apple-seed-size critters for yourself. Unfortunately, once bedbugs take up residence in homes and businesses, they can be difficult to exterminate without professional help.
It’s perfectly natural to want to eliminate a bed bug infestation without spending a ton of money on professional-grade products or a treatment by a pest control operator. When people discover that they have bed bugs, they often turn to do-it-yourself recommendations from discussions on the Internet. These suggestions might include household items, some of which are recommended more often than others. Let’s take a closer look at some of the most popular items and how they might be used against bed bugs:
When professionals need to treat an infestation, they don’t reach for rubbing alcohol or cedar oil or a blow dryer. They use a proven treatment process that involves a combination of proven products to get the job done. It’s not about whether or not a certain item can kill bed bugs, it’s about whether that item is the ideal part of a treatment that will actually get rid of an infestation. After all, your shoe would have a 100% kill rate on any bed bugs you smack with it – that doesn’t mean you can expect to be bed bug free after a diligent afternoon of shoe-wielding.
“Good night, sleep tight, don’t let the bed bugs bite.” This horrific nighttime creature is a member of the Hemiptera order of insects that feast solely on blood. Because of the way they mate, they multiply in size while breeding. A Department of Health report claimed that if forty are placed in a room with a mild temperature, within six months their population would exceed 5,900.
2. Active Guard Liners: Active Guard Mattress Liners may be placed on beds and are effective as both preventative and active bed bug treatments. They kill bed bugs and dust mites within 72 hours and will prevent bed bugs from infesting mattresses. ActiveGuard Liners act like a fitted sheet; it comes in single, full, queen, and king sizes that fit up to 17" in depth.
Bedbugs are highly resistant to many sprays. There are, however, certain sprays that may be able to kill bedbugs. Check with a professional exterminator about advice using sprays to try and remove the bedbugs yourself. Dead bedbugs usually won't move, may be arched back, or red in color. Ultimately, you may be better off replacing your mattress and bedding and fumigating your home to kill the bedbugs.

They also have the ability to travel beyond the bedroom, so all adjoining rooms should be checked for infestation. Any area that offers a layer of protection, e.g. dark, isolated areas, should be checked. They do leave excrement droppings behind, so even if they are not seen, you can often see where they have been. The best method to find them is to check only at night, and with a red light.

Wash all the clothing that you brought home in a washing machine. Even clothes that you didn't wear must be washed in hot water. If you cannot wash something in a washing machine, you can either place it in a hot dryer or seal the items in a plastic garbage bag. If you seal items in a  garbage bag, leave the bag securely closed in an extremely cold or hot place for a few months.
To use sprays effectively to eliminate all traces of bed bugs, you need to know the signs of a bed bug infestation. The first sign that you may have bedbugs are some itchy bite marks on your skin when you wake up in the morning. Dr. Carol DerSarkissian on WebMD says that the bites from bed bugs cause red itchy bumps on the skin.3 You can learn about their other signs and symptoms in my articles on what do bed bug bites look like.
Pesticides should always be used with caution, and especially when used indoors.  Never use a pesticide for bed bugs that does not bear clear directions stating that it can be used indoors.  Never spray yourself, children or pets with a pesticide.  And follow the label safety directions carefully.  Pesticide labels contain directionsfor use that are not merely suggestions.  Failure to follow directions exactly is illegal and can result in poor control and possible harm to yourself and family.  For more information, see the EPA Consumer Alert on pesticides and bed bugs.
It’s perfectly natural to want to eliminate a bed bug infestation without spending a ton of money on professional-grade products or a treatment by a pest control operator. When people discover that they have bed bugs, they often turn to do-it-yourself recommendations from discussions on the Internet. These suggestions might include household items, some of which are recommended more often than others. Let’s take a closer look at some of the most popular items and how they might be used against bed bugs:
I have a situation were I have been infested in my room,I have been beaten and I have red spots all over my body, is itching at night and affected my sleeping time, I spoke to the landlord to get a treatment but they dont seem to care much, should I move to a diferent place? What do I need to do in order not to be follow into the new place? Any recomendation out there?

Bed bugs occur around the world.[36] Before the 1950s about 30% of houses in the United States had bedbugs.[2] Rates of infestations in developed countries, while decreasing from the 1930s to the 1980s, have increased dramatically since the 1980s.[3][4][36] Before the 1980s they were common in the developing world but rare in the developed world.[4] The increase in the developed world may have been caused by increased international travel, resistance to insecticides, and the use of new pest-control methods that do not affect bed bugs.[37]
Bed bugs are very hardy insects. Both adults and nymphs can survive prolonged periods without food or under adverse temperature conditions. Adults can live for a year or longer without feeding and can survive over winter in an unheated building. Nymphs are not as hardy as adults, but they can survive for considerable periods under adverse conditions.
Bedbugs are highly resistant to many sprays. There are, however, certain sprays that may be able to kill bedbugs. Check with a professional exterminator about advice using sprays to try and remove the bedbugs yourself. Dead bedbugs usually won't move, may be arched back, or red in color. Ultimately, you may be better off replacing your mattress and bedding and fumigating your home to kill the bedbugs.
Great read and very helpful info. However, when you describe how to use essential oil sprays for bed bug treatment, it would be most helpful if you included the amount of water used to mix with the oils. Simply stating to use “a small spray bottle filled with water” isn’t a very good description. A quick search for “small spray bottle” will get results for a wide range from 2-ml to 16-ounce bottles, all classified as small. This makes for a rather potent mixture to an extremely weak mixture.
Avoiding bed bugs is most challenging in hotels, apartment buildings, and other places where there are many people, high turnover and ongoing opportunities for introduction of the pests. Periodic, preventive inspection by tenants, housekeeping/maintenance staff, or pest control firms is the best way to detect infestations in their initial stages when they are easiest to control. Visual inspections can be supplemented by using various monitoring devices to capture and reveal bed bugs that may have been overlooked by occupants.   

Bedbugs are highly resistant to many sprays. There are, however, certain sprays that may be able to kill bedbugs. Check with a professional exterminator about advice using sprays to try and remove the bedbugs yourself. Dead bedbugs usually won't move, may be arched back, or red in color. Ultimately, you may be better off replacing your mattress and bedding and fumigating your home to kill the bedbugs.
If the bed bugs are coming from someplace other than your bed, I’d sprinkle uncalcinated diatomaceous earth around cluttered areas and the walls, and bleach the crap out of surrounding furniture. What the diatomaceous earth does is basically attach to their exoskeleton, dehydrate the insect, and they’ll either die of dehydration or get shredded apart as they crawl. Unless your pet or kid would directly eat the diatomaceous earth, it is safe to be in contact with since it’s not a chemical pesticide and it’s fairly cheap.
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Bed bugs multiply quickly, and in just six months, a few can turn into a full-on infestation of 13,000 or more. Detection is critical to break the bed bug life cycle before they become a bigger problem. Orkin Bed Bug Detection Service gets to the root of the problem with targeted inspections of common bed bug hiding places in your home and ongoing monitoring to ensure the pests never return.
Bed bugs like to travel and are good hitchhikers. They will hide in suitcases, boxes and shoes to be near a food supply. They are elusive, nocturnal creatures. They can hide behind baseboards and in cracks, crevices, and folded areas of beds, bedding and adjacent furniture, especially mattresses and box springs. Bed bugs can also hide in electrical switchplates, picture frames, wallpaper and nearly anywhere inside a home, car, bus, or other shelter. Bed bugs usually come out at night for a blood meal. However, they are opportunistic insects and can take a blood meal during the day, especially in heavily-infested areas. Bed bugs usually require 5-10 minutes to engorge with blood. After feeding, they move to secluded places and hide for 5-10 days. During this time in the bed bug life cycle, they do not feed but instead digest their meal, mate, and lay eggs.
Vigilant travelers may also want to elevate suitcases off the floor on a stand, tabletop or other hard surface rather than storing them on the floor or another bed. Hyper-vigilant travelers may further opt to keep belongings in sealed plastic pouches and their suitcase in a zippered tote — however each traveler must decide how cautious they wish to be. 

Turns out, C. lectularius is also forming a resistance to other insecticides, according to a study published online April 10, 2017, in the Journal of Economic Entomology. The researchers, from Purdue University, found that three out of 10 bedbug populations collected in the field showed much less susceptibility to chlorfenapyr, and five of the 10 populations showed reduced susceptibility to bifenthrin, according to a post on Entomology Today. The scientists defined "reduced susceptibility" as a population in which more than 25 percent of the begbugs survived after seven days of exposure to the particular insecticide.
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