The effective use of pesticides for bed bug control typically involves a thorough inspection during which the technician will kill any bed bugs he/she discovers, applying contact or residual pesticides directly on the bugs. This is followed by residual application to all cracks, crevices and voids, likely to harbor bed bugs. The pesticide used should be one that remains active for weeks, allowing bed bugs that were missed on the initial inspection to contact treated surfaces long enough to receive a lethal dose.
Bed bugs are attracted to their hosts primarily by carbon dioxide, secondarily by warmth, and also by certain chemicals.[4][16][17][18] Cimex lectularius only feeds every five to seven days, which suggests that it does not spend the majority of its life searching for a host. When a bed bug is starved, it leaves its shelter and searches for a host. It returns to its shelter after successful feeding or if it encounters exposure to light.[19] Cimex lectularius aggregate under all life stages and mating conditions. Bed bugs may choose to aggregate because of predation, resistance to desiccation, and more opportunities to find a mate. Airborne pheromones are responsible for aggregations.[20]

Although bedbugs are generally nocturnal, they're like humans—if they're hungry, they'll get up and get something to eat. "If you go away to visit a friend for a week and you come back and sit down on the couch, even though it's daytime the bedbugs will come looking for you," Schal says. Keeping a light on, then, unfortunately does not keep these tiny vampires away.
Stripping and vacuuming the mattresses and box springs, and encasing them.  Double bag your bedding and wash in hot water and dry for at least 30 minutes (discard the inner bag after putting bedding into the washer, as it could have bed bugs).  After vacuuming suspected bed bugs from the bed, take your vacuum cleaner outdoors and remove and discard the bag.  Purchase a good quality set of bed-bug-proof encasements for your mattresses and box springs. Bed bug-proof encasements are fabric sacks into which you slide your mattress or your box spring. The zippers on bed bug encasements are designed to be tight enough to prevent even the smallest life stages of the bed bugs from escaping. Also, good bed bug-proof encasements are woven to prevent bed bugs from biting you through the encasement. A good encasement will trap all bed bugs in the mattress and box spring inside, and will be smooth on the outside, providing few places for bed bugs to hide. Sears, Target, Walmart and other stores may sell bed bug-proof encasements, but these can also be purchased online. A good place to look for different brands and reviews of mattress encasements is Amazon.com (whether you buy there or at a local store). Go to http://www.amazon.com and search for “bed bug mattress protectors”.
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