Because bed bug bites affect everyone differently, some people may have no reaction and will not develop bite marks or any other visible signs of being bitten. Other people may be allergic to the bed bugs and can react adversely to the bites. These allergic symptoms can include enlarged bite marks, painful swellings at the bite site, and, on rare occasions, anaphylaxis.
Both of these types of Hemiptera are sensitive to extreme temperatures. It may be necessary to rid the infestation by exposing the area to extreme heat or cold; they are most comfortable in temperatures around eighty degrees Fahrenheit. Raising the temperature to ninety-seven to ninety-nine degrees may kill off a significant portion of the population.
The size of bed bug bites varies with a number of different factors. Bed bugs inject an anti-coagulant along with their saliva when they pierce the skin to take a blood meal. This anti-coagulant is mostly responsible for how a person reacts to the bite and determines the size of the bug’s bite. Since people will have various sensitivities to the bed bug’s bite, the size of the bite will vary, as well. Another factor that influences the size of a bed bug reaction is the number of times a person is bitten. Bite reactions of people bitten many times are also variable, and their response may be either more or less intense as the number of bites increases.
^ Kambu, Kabangu; Di Phanzu, N.; Coune, Claude; Wauters, Jean-Noël; Angenot, Luc (1982). "Contribution à l'étude des propriétés insecticides et chimiques d'Eucalyptus saligna du Zaïre (Contribution to the study of insecticide and chemical properties of Eucalyptus saligna from Zaire ( Congo))". Plantes Médicinales et Phytothérapie. 16 (1): 34–38. hdl:2268/14438.
Bed bugs are experts at hiding. Their slim flat bodies allow them to fit into the smallest of spaces and stay there for long periods of time, even without a blood meal. Bed bugs are usually transported from place to place as people travel. The bed bugs travel in the seams and folds of luggage, overnight bags, folded clothes, bedding, furniture, and anywhere else where they can hide. Most people do not realize they are transporting stow-away bed bugs as they travel from location to location, infecting areas as they travel.
Itchy swollen bites may be the first sign of a bed bug problem. However, these itchy bites can take as long as 14 days to develop in some people, so it's important to look for other clues if you are concerned about an infestation. Bed bugs typically infest mattresses, box springs, bed frames, and couches. You may be able to find them hiding within the cracks and crevices of beds, furniture, floors, and walls. Bed bugs often leave evidence of small dark stains (fecal droppings) and rusty red spots (bloodstains) on bedding sheets, mattresses, and other areas they hide in or travel along. Heavy bed bug infestations can cause a sweet, musty smell.
Fumigation using a penetrating gas is another way to de-infest dwellings or furnishings, but the procedure is only offered by certain companies. True fumigation is not the same as setting off a total release fogger or ‘bug bomb.’ (It should be noted that bug bombs are considered ineffective in the treatment of bed bugs, and can be quite dangerous if misused.) The fumigation process is technically complex and requires vacating the building for a period of days. The building is then sealed and injected with a lethal gas, usually sulfuryl fluoride. Because the entire building must be vacated, structural fumigation is logistically more challenging with multi-unit buildings such as apartments, than for single family homes. Bed bug fumigations tend to be more common in southern and western states, where the procedure is also used to control certain types of wood-dwelling termites.  

Bed bugs are very resilient. Nymphs and adults can persist months without feeding which is unusual for most insects. The ability to survive without a blood meal is longer at cooler temperatures ― potentially up to a year or longer at 55°F or less. In temperature-controlled buildings, a more typical duration is about 2 to 6 months. Consequently, it is usually impractical to leave buildings unoccupied in hopes of ‘starving out’ an infestation. When infested dwellings such as apartments are vacated, bed bugs often disperse to nearby units, or reduce their activity until the unit is reoccupied. 
Some patients develop blisters filled with blood or bloody fluid, especially on the arms and legs. These blood blisters are extremely rare and can burst, causing bleeding or oozing of the bloody fluid. Healthcare providers are not sure if the cause of these blisters is related to the bug or the human but have found groups of patients that were all bitten by bugs on the same train exhibiting this sign.
It is difficult to tell bedbug bites from those of mosquitoes, fleas, or other insects. You likely won't feel bedbugs biting as they inject an anesthetic and anticoagulant when they bite. You may develop bite marks one to 14 days after being bitten. As with mosquitoes, their saliva can provoke an allergic reaction at the site of the bite. Some people have no reaction, others have a mild one, while some can have significant swelling.
I have had one bite in threes which cleared up in days and an occasional acne looking sore on my but and arm. I have noted in my car lots of little bites but no marks. My son does not appear to have bites. once he had one on his back that cleared quickly. I really needs some help here as I am getting obsessive with cleaning and making my child change and bath. I have checked my cat for flees and bought her a flee collar as I am thinking the stinging bites I get in the day may be from flees but no itch or real marks. Help please.
When you return home, quarantine your bags. Decontaminate your luggage and clothing by putting your entire suitcase into a large chest freezer (if you have one) for four days, suggests Gondhalekar, before bringing them back into your home. Extreme hot or cold temperatures kills bed bugs. You can also put your clothes in the dryer on a hot setting for 30 minutes, and try steam cleaning your luggage and clothing.
Do encasements work? Yes. When you put an encasement on your mattress or box spring you can lock bed bugs in and prevent new bed bugs from getting in. No chemical control is needed, so you don't have to worry about being poisoned by powders or some other toxin in your bed. The problem is that encasements by themselves, or when used with traps, are simply a bandaid. They are not likely to contain or stop a bed bug infestation. As mentioned above, this method can lead to the growth of an infestation and, ultimately, a prolonged and frustrating infestation.
2. Active Guard Liners: Active Guard Mattress Liners may be placed on beds and are effective as both preventative and active bed bug treatments. They kill bed bugs and dust mites within 72 hours and will prevent bed bugs from infesting mattresses. ActiveGuard Liners act like a fitted sheet; it comes in single, full, queen, and king sizes that fit up to 17" in depth.

Bedbugs are highly resistant to many sprays. There are, however, certain sprays that may be able to kill bedbugs. Check with a professional exterminator about advice using sprays to try and remove the bedbugs yourself. Dead bedbugs usually won't move, may be arched back, or red in color. Ultimately, you may be better off replacing your mattress and bedding and fumigating your home to kill the bedbugs.
These nocturnal creatures can hide in beds, floors, furniture, wood, and paper trash during the day. We humans usually become their dinner during the night, with peak biting activity just before dawn.They can obtain their meal in as little as three minutes, after which they are engorged and drop off the host, then crawl into a hiding place to digest their meal. Bedbugs can live for 10 months, and can go weeks without feeding.
Bed bug infestations are primarily the result of two species of insects from genus Cimex: Cimex lectularius (the common bed bug) and Cimex hemipterus.[3] These insects feed exclusively on blood and may survive a year without eating.[3] Adult Cimex are light brown to reddish-brown, flat, oval, and have no hind wings. The front wings are vestigial and reduced to pad-like structures. Adults grow to 4–5 mm (0.16–0.20 in) long and 1.5–3 mm (0.059–0.118 in) wide.
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