You’ll likely only see them in their hiding spots or crawling across the floor since, unlike other insects, bedbugs cannot fly or jump. Durham says to check along the edges of your mattress. You may see the exoskeletons that bedbugs have shed as they matured, or you may notice a musty smell, both of which indicate there could be bedbugs in the area. It can also be helpful to check your bed with a flashlight during the middle of the night (since these crawlers tend to be more active at night.)
Low toxicity contact sprays like SteriFab™ or Bedlam® are likely to kill bed bugs only on contact. Alcohol- and soap-based sprays, are only partly effective. All of these products, once dry, are likely to provide no further control. Eggs will not be killed by alcohol-based sprays, so repeat treatments are usually needed. Be careful when using sprays containing alcohol because they may be flammable.
Once you’ve vacuumed and chemically treated your mattress and box spring, enclose them in encasement bags. If the bed bugs found a way inside the mattress, the odds are that the spray chemicals did not kill them. Encasement bags have special zippers that trap the bed bugs and prevent them from escaping. Keep these bags on for at least a year because a fully fed bed bug can live more than 10 months between meals.
The Diatomaceous Earth seems to kill them and centipedes. Didn’t even know I had those til I put powder down to prevent bed bugs and found one curled up dead. It dries them out and kills them. Works great! I’ve heard boric acid doesn’t work on bed bugs but I do know it works wonders on killing roaches. My sister had them in an apartment & boric acid wiped them out! 

If you live in an apartment or condominium, it’s best to alert the property manager.  A coordinated bed bug control effort using a pest control company is generally needed in such situations. Bed bugs readily move from apartment to apartment, with many people unaware that they have a problem. If one apartment is infested, adjoining units (left side, right side, above and below) should be assumed to be infested unless shown otherwise through inspection or monitoring.  Simply asking tenants whether they have bed bugs is not enough.  In one recent study only half of apartment residents whose homes were determined to have bed, bugs knew (or admitted) they had a bed bug problem.
Use precautions in your own home. Keep the plastic covering that comes on your mattress when purchased new. Purchase special bedbug covers for you mattress and box spring. Make sure that they are quality ones with heavy duty zippers and constructed with special fabric that doesn't rip easily. Don't buy the cheap versions which are not thick enough to prevent the bedbugs from sticking their feeding tubes into the skin through the cover.[19]

Checking beds for bed bugs was a common practice long ago, especially while traveling. Travelers today should consider doing the same, preferably before unpacking. This would entail examining the bed sheets and seams of the mattress and perhaps box spring for signs of bed bugs, especially along the head (pillow end) of the bed. Experts also remove and check behind headboards since this is a frequent hiding place for bed bugs in hotels. Headboards are heavy and cumbersome, however, and untrained persons should not attempt removal themselves.
Doctors often misdiagnose those afflicted because it is nearly impossible to tell, if you are experiencing an allergic reaction, what bit you. Often healthcare providers and individuals that have been bitten by a member of the Hemiptera order mistake bites for those of a mosquito. The only way to discern, with complete surety, what your bites are from, is to get a sample of what has bitten you.
Once you’ve vacuumed and chemically treated your mattress and box spring, enclose them in encasement bags. If the bed bugs found a way inside the mattress, the odds are that the spray chemicals did not kill them. Encasement bags have special zippers that trap the bed bugs and prevent them from escaping. Keep these bags on for at least a year because a fully fed bed bug can live more than 10 months between meals.
The likelihood of bed bugs increases if the affected individual has been traveling, or if they have acquired used beds or furnishings before symptoms started to appear. Bed bugs also are suspect if you wake up with itchy welts you did not have when you went to sleep. It’s important to recognize, however, that not all bite-like reactions are due to bed bugs. Confirmation requires finding and identifying the bed bugs, shed skins, fecal spots, etc., which often requires the help of a professional. (Other possible sources of irritation that may be mistaken for bed bugs are discussed in University of Kentucky entomology fact sheet ENT-58, Invisible Itches: Insect and Non-Insect Causes). 
Bedbugs normally feed at night, usually approximately 1 hour before dawn. However, if the conditions are favorable, they also feed during the day. Feeding takes 3-12 minutes. In proper conditions, adult bedbugs can survive without a meal for 1 year or longer. Each female lays approximately 300 eggs in her lifetime. The eggs hatch in 10 days. The nymph stage lasts 6 weeks, undergoing 5 molts.
The mechanism of skin injury by arthropods depends on the structure of the mouthparts. These insects are categorized as vessel feeders if they insert the tip into a capillary or as pool feeders if they feed on the extravasated blood from damaged tissue. They often inject different pharmacologically active substances (eg, hyaluronidase, proteases, kinins), which may cause different skin reactions (eg, erythema, wheal, vesicle, hemorrhagic nodule). See the following images.
The decline of bed bug populations in the 20th century is often credited to potent pesticides that had not previously been widely available.[44] Other contributing factors that are less frequently mentioned in news reports are increased public awareness and slum clearance programs that combined pesticide use with steam disinfection, relocation of slum dwellers to new housing, and in some cases also follow-up inspections for several months after relocated tenants moved into their new housing.[66]
 Adult bed bugs are about 3/16” long and reddish-brown, with oval-shaped, flattened bodies. They are sometimes mistaken for ticks, cockroaches, carpet beetles or other household insects. The immature bed bugs (nymphs) resemble the adults, but are smaller and lighter in color. Bed bugs do not fly, and they don’t jump like fleas do ― but they can crawl rapidly over floors, walls, ceilings and other surfaces. Adult females lay their eggs in secluded places, depositing 1, 2 or more eggs per day, potentially hundreds during their lifetime. The eggs are tiny (about the size of a dust spec), whitish and hard to see without magnification, especially on light-colored surfaces. When first laid, the eggs are sticky, causing them to adhere to surfaces. At room temperatures, bed bug eggs hatch in about a week. Newly emerged nymphs are straw-colored and no bigger than a pinhead.

Bedbugs may enter your home undetected through luggage, clothing, used beds and couches, and other items. Their flattened bodies make it possible for them to fit into tiny spaces, about the width of a credit card. Bedbugs do not have nests like ants or bees, but tend to live in groups in hiding places. Their initial hiding places are typically in mattresses, box springs, bed frames, and headboards where they have easy access to people to bite in the night.


While your laundry cycle is running, use a vacuum cleaner to remove any bed bugs, shells, fecal droppings, or eggs that might be along the seams of your mattress, pillows, box spring, and along the cracks and crevices in the bed frame, headboard, and footboard. Follow up the vacuuming with a high pressure steamer to penetrate deep inside mattresses, box springs, bed frames, headboards, and footboards to kill bed bugs and eggs on contact.
Doctors often misdiagnose those afflicted because it is nearly impossible to tell, if you are experiencing an allergic reaction, what bit you. Often healthcare providers and individuals that have been bitten by a member of the Hemiptera order mistake bites for those of a mosquito. The only way to discern, with complete surety, what your bites are from, is to get a sample of what has bitten you.
Stripping and vacuuming the mattresses and box springs, and encasing them.  Double bag your bedding and wash in hot water and dry for at least 30 minutes (discard the inner bag after putting bedding into the washer, as it could have bed bugs).  After vacuuming suspected bed bugs from the bed, take your vacuum cleaner outdoors and remove and discard the bag.  Purchase a good quality set of bed-bug-proof encasements for your mattresses and box springs. Bed bug-proof encasements are fabric sacks into which you slide your mattress or your box spring. The zippers on bed bug encasements are designed to be tight enough to prevent even the smallest life stages of the bed bugs from escaping. Also, good bed bug-proof encasements are woven to prevent bed bugs from biting you through the encasement. A good encasement will trap all bed bugs in the mattress and box spring inside, and will be smooth on the outside, providing few places for bed bugs to hide. Sears, Target, Walmart and other stores may sell bed bug-proof encasements, but these can also be purchased online. A good place to look for different brands and reviews of mattress encasements is Amazon.com (whether you buy there or at a local store). Go to http://www.amazon.com and search for “bed bug mattress protectors”.
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