Encase Mattresses and use bed bug interceptor traps on bed frames. After everything is put back and all pesticides are dried, vacuum the area again to remove any dead or dying bedbugs and to pick up any spilled dust or pesticide. Be sure to throw the vacuum cleaner bag away outdoors. A thorough treatment is essential to achieve adequate control. It is usually desirable to apply insecticides for bed bugs early in the day, so that insecticide spray residues will have several hours to dry, or dusts will have time to settle, before the room will be used again for sleeping. As a safety consideration it is particularly important to dry and cover mattresses completely before they are reused. A mattress encasement such as The Elite Zippered Mattress and Boxspring Encasement should be used to cover and conceal the mattress and the boxsprings. It is important to use a quality zippered encasement (cover) with a special zipper closure to make sure that bedbugs do not crawl out of the zipper opening.
Treat or isolate your bagged items. For washable items research shows that dry cleaning, washing in hot water for 30 minutes, or tumble drying for 30 minutes on high will kill all stages of bed bugs. Non-washables are a little trickier.  Items that aren’t needed for a while can just be stored. It takes 2-5 months to kill bed bugs by isolating them in bags (the warmer the temperature, the shorter the survival time for starving bed bugs). Heating bags by placing in direct sunlight is one of the most effective methods during the warm summer months.  Seven pounds of items placed in clear bags in direct sunlight on a 95 degree day will get hot enough to kill all bed bug life stages in one afternoon.  Also, placing bagged items in a chest freezer (0 degrees F) for 8-10 hours is lethal for bed bugs and their eggs. Some toys may be disinfested by cleaning with hot soapy water and/or rubbing alcohol.
Bites on dogs and cats will look much like bites on people, and the pet owner may actually suspect a mosquito or flea bit the pet. As with people, bed bugs do not stay on pets, but return to a protected harborage site after feeding. In addition to bites, the presence of the bug’s feces, cast skins and the animal’s irritation at night are also indicators of bed bugs biting pets. Therefore, one of the best things to do is inspect the pet’s bedding and frequently groom the animal while being vigilant for the telltale signs of bed bug presence.
People don't often consider bed bugs until they've left their mark. The appearance of flat, red welts in zigzag lines or small clusters is a key sign of bed bugs on humans. Bed bugs can also leave their bites in straight rows and, while they don't spread diseases to humans, their bites are quite irritating and scratching them can lead to bleeding and infection.
You’ll likely only see them in their hiding spots or crawling across the floor since, unlike other insects, bedbugs cannot fly or jump. Durham says to check along the edges of your mattress. You may see the exoskeletons that bedbugs have shed as they matured, or you may notice a musty smell, both of which indicate there could be bedbugs in the area. It can also be helpful to check your bed with a flashlight during the middle of the night (since these crawlers tend to be more active at night.)
Apply residual Bed Bug Insecticide Spray. After every crack, crevice, switch plate, electrical switch, baseboard, box springs, mattress, etc, has been treated and everything is put back, it is time for the residual treatment. Using a hand held sprayer such as the Chapin Sure Spray apply Optimate, Cy-Kick, Suspend SC or Demand along the baseboards in the bedroom and closet, under and around the bed, behind the headboard, inside bed stands etc.
Dogs have been sniffing out insects such as termites for many years, and are now being used as inspection tools for bed bug detection. But while companies using dogs may advertise them as being highly accurate in finding bed bugs, one should not get the impression that dogs are infallible or that they are in all ways superior to human inspectors. Research on the effectiveness of dogs as bed bug detectors suggests that for those who would employ dogs, the message is buyer beware. There appears to be great variance in the accuracy of bed bug dogs, and even well-trained dogs are subject to missing bed bugs and to giving “false positives” (signaling the presence of bed bugs where there are none).
Bring in only what is needed, and avoid sitting or placing coats and other items on beds, floors and sofas where the bugs commonly reside. Essential items can be placed on a tabletop or other hard surface, preferably away from bedrooms and sleeping areas. Better to sit on a hard (non-upholstered) chair than on sofas and recliners. Also try to avoid leaning or brushing against beds and upholstered furniture. If such items are carried out of infested dwellings (e.g., by sanitation workers or firefighters), it’s best to wrap them in plastic or at least not hold them against your body during transport. Emergency Medical (EMS) personnel may need to take additional precautions, such as removing a patient’s bed bug-infested shoes or clothing, or installing plastic sheeting before transporting them in the emergency vehicle.    
Research has shown that some bed bugs are resistant to the pyrethroid pesticides that have been most commonly used in recent years by pest management professionals. Likewise, pyrethroids such as deltamethrin and permethrin have been among the active ingredients most commonly available in pesticides at retail stores. The ongoing use of pyrethroids has undoubtedly contributed to the resistance we see today in some bed bug populations.
A flashlight:  Bed bugs hide in dark areas and in cracks and crevices.  Bed bugs are a dark red to brown color, but they can be light brown if they haven’t been feeding. This makes it very hard to see them. When hunting for bed bugs hold your flashlight parallel to the surface being inspected, this will cause eggs and small bed bugs to cast a shadow, making them easier to find.
Bed bugs are very resilient. Nymphs and adults can persist months without feeding which is unusual for most insects. The ability to survive without a blood meal is longer at cooler temperatures ― potentially up to a year or longer at 55°F or less. In temperature-controlled buildings, a more typical duration is about 2 to 6 months. Consequently, it is usually impractical to leave buildings unoccupied in hopes of ‘starving out’ an infestation. When infested dwellings such as apartments are vacated, bed bugs often disperse to nearby units, or reduce their activity until the unit is reoccupied. 
Reactions to bed bug bites vary among individuals. Many persons show no signs of bites. Others don’t realize they’ve been bitten until redness and swelling appear around the bite, sometimes with intense itching. Some exhibit inflamed swollen spots that may occur in linear series or have a rash-like appearance. Such bite marks, when they appear, may not show for several days after the person is bitten.
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