To use sprays effectively to eliminate all traces of bed bugs, you need to know the signs of a bed bug infestation. The first sign that you may have bedbugs are some itchy bite marks on your skin when you wake up in the morning. Dr. Carol DerSarkissian on WebMD says that the bites from bed bugs cause red itchy bumps on the skin.3 You can learn about their other signs and symptoms in my articles on what do bed bug bites look like.
Pesticides alone are not the answer to bed bugs. Most of the commonly used pesticides today, including professional products and consumer products advertised for control of bed bugs, are at best moderately effective at controlling these pests. Pesticides must be used with care for safety and with attention to proper application to work well. Aerosol “bug bombs” or “fumigators” are also mostly ineffective in eliminating bed bugs. Aerosol insecticides mainly kill insects that are exposed, and out of their hiding places, not those hidden behind baseboards, in cracks and crevices of the bed, under carpet edging and in walls.
Once a pest of the past, bedbugs now infest every state in the U.S.. Cimex lectularius—small, flattened insects that feed solely on mammalian and avian blood—have been living with humans since ancient times. Abundant in the U.S. prior to World War II, bedbugs all but vanished during the 1940s and '50s thanks to improvements in hygiene and the use of pesticides. In the past 10 years, however, the pests have staged a comeback worldwide—an outbreak after the 2000 Summer Olympics in Sydney was a harbinger of things to come. This revival may be the worst yet, experts say, due to densely populated urban areas, global travel and increasing pesticide resistance—something to consider as the summer travel season gets underway.
To begin, strip your bed of all sheets, pillowcases, and other bedding, and seal them in plastic garbage bags to keep bed bugs from escaping and infesting other parts of your home. Take the bags straight to the washing machine, and wash them using the hot water setting. Then, dry the bedding on high heat if their tags allow it. This heat treatment will kill any bed bugs or eggs hiding in your bedding.
Bed bugs are experts at hiding. Their slim flat bodies allow them to fit into the smallest of spaces and stay there for long periods of time, even without a blood meal. Bed bugs are usually transported from place to place as people travel. The bed bugs travel in the seams and folds of luggage, overnight bags, folded clothes, bedding, furniture, and anywhere else where they can hide. Most people do not realize they are transporting stow-away bed bugs as they travel from location to location, infecting areas as they travel.
Reality: Bedbug control can only be maintained through a treatment strategy that includes a variety of techniques plus careful attention to monitoring. Proper use of pesticides may be part of the strategy, but will not by itself eliminate bedbugs. In addition, bedbug populations in different areas of the country have developed resistance to the ways many pesticides work to kill pests. If you're dealing with a resistant population, some products and application methods may not work. It is a good idea to consult a qualified pest management professional if you have bedbugs in your home.
To know it's bedbugs, it's important to find the bugs themselves. Look at bedsheets and mattresses for little spots of blood, rusty-looking stains (crushed bugs), or black dots (bugs' poop). You might see live bugs around the seams or tags of mattresses and box springs, or in cracks of bed frames and other furniture. They can even hide in books, carpet edges, and electrical outlets.
While the mattress and box spring are left to dry, spray down the joints of the bed frame, headboard, and footboard with a contact spray and residual spray. The contact spray will kill bed bugs quickly and then evaporate, while the residual spray will kill bed bugs over several weeks. Remember to follow the sprays’ product labels and MSDS for safe and effective usage.

Buy “say bye bugs” I think its liquid diatemacious earth food grade, I put powder down on my couch took all loose wood off and they were hidden under material sprayed and dusted it with the diatemacious earth kills them on contact, of course you have to do it 10 days. Because even dead they can lay eggs……keep spraying every day, wash bedding in hot water dry at least 45 min on high heat, after you think they are dead, put mattress or furniture in bed bug bag for a year, because they can stay alive for a year without eating…om working on it going on 3 days now!!
I paid $1200 for extermination heat treatment- lasted a few months and they are back- bought all new furniture! Still bugs- spray bye bye bugs spray which kills on contact but didn’t stop the infestation! This is going on 2 years now!!!! Mainly they are just in the 2 bedrooms. Ours and one that hardly no one sleeps in. But when grandkids come- they get bitten bad- I scrub, spray, vacuum & steam clean, & wash all bedding n still bit!!! Ready to burn the house down!!! HELP!!!!!! Can’t afford another $1200 

We have used Orkin on 2 occasions and have had 100% satisfaction on both Bed Bugs and Carpenter Ants. Both of the Technicians were very knowledgeable, courteous and were concerned about how we felt about the situation. My wife's father had a very bad case of Bed Bugs, which is where we got them from, and we referred Orkin and as now there are no signs of bugs at his house.
Monitor Bed Bug movement with Traps. Bed Bug traps don't work to control bed bugs - they only monitor bed bug movement. Try using Catchmaster 288i Professional Bug Traps by placing them against walls, behind furniture, sticking them under bedframes (yes they work upside down), and anywhere you think bed bugs could be crawling to get back to the bed. Inspect these traps every few days. If you capture bed bugs, then you may have to retreat and do this entire procedure over again. If the traps are empty, then pat yourself on the back for a job well done, but don't think that bed bugs are gone forever. They could be walking around the trap or just waiting for the comforter to hit floor before they climb back into bed!
To get rid of bed bugs in a mattress, use an aerosol spray labeled for bed bug treatment, such as Bedlam Aerosol Spray, and spray or mist the insecticide onto the mattress. Focus on the seams, tufts, and folds of the mattress and spray until the mattress is damp. Allow mattress to dry before remaking the bed with freshly laundered sheets that have been run through a dryer on high heat.
I'm a former scientist, using words and an audio recorder as my new research tools to untangle the health and food issues that matter most to consumers. I live in Brooklyn, N.Y., where I cook as much as possible. You can find me in the grocery aisle scrutinizing the fine print of every food item I put into my cart. Follow me on Twitter @juliacalderone.

Repeat this same search with the box-spring.  The only difference is that box-springs usually have plastic edge guards and a loose fabric called “ticking” stapled on the underside.  These seams and edges on the underside of the box-spring are very common hiding places for bed bugs.  To ensure there are no bed bugs inside the box-spring, you should remove the ticking and check the wood, cracks and crevices, and screw holes within.  After inspection, the ticking can be re-stapled in place.  

Bed bug bites are caused primarily by two species of the insect Cimex: Cimex lectularius (the common bed bug) and Cimex hemipterus.[3] Their size ranges between 1 and 7 mm.[7] They spread by crawling between nearby locations or by being carried within personal items.[2] Infestation is rarely due to a lack of hygiene but is more common in high-density areas.[8][2] Diagnosis involves both finding the bugs and the occurrence of compatible symptoms.[5] Bed bugs spend much of their time in dark, hidden locations like mattress seams or cracks in the wall.[2]
Stripping and vacuuming the mattresses and box springs, and encasing them.  Double bag your bedding and wash in hot water and dry for at least 30 minutes (discard the inner bag after putting bedding into the washer, as it could have bed bugs).  After vacuuming suspected bed bugs from the bed, take your vacuum cleaner outdoors and remove and discard the bag.  Purchase a good quality set of bed-bug-proof encasements for your mattresses and box springs. Bed bug-proof encasements are fabric sacks into which you slide your mattress or your box spring. The zippers on bed bug encasements are designed to be tight enough to prevent even the smallest life stages of the bed bugs from escaping. Also, good bed bug-proof encasements are woven to prevent bed bugs from biting you through the encasement. A good encasement will trap all bed bugs in the mattress and box spring inside, and will be smooth on the outside, providing few places for bed bugs to hide. Sears, Target, Walmart and other stores may sell bed bug-proof encasements, but these can also be purchased online. A good place to look for different brands and reviews of mattress encasements is Amazon.com (whether you buy there or at a local store). Go to http://www.amazon.com and search for “bed bug mattress protectors”.
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