Monitor your home. Bed bugs like to hide in cracks and crevices like walls, luggage, boxes, and clothing, but since they feed on humans while they sleep, they’re most commonly found in beds. If you suspect an infestation, or if you live in an apartment building with a bed bug problem, regularly inspect your bed sheets, mattress (including underneath), and box-spring seams for bugs. They’re flat and oval-shaped, with red or brown bodies, roughly the size of an apple seed. Watch for adults, nymphs, and eggs, as well as exoskeletons (casings that the bugs leave behind when they molt) and dark, rust-colored spots (feces).
Some bed bug species are parasites of bats or birds, and may bite people if the wild hosts are no longer available. Although similar in overall appearance, the species of bed bugs that normally feed on bats, swallows, chimney swifts, pigeons or other wild hosts can be differentiated from those that prefer humans. Entomologists and knowledgeable pest managers can make this determination. If bat bugs or bird bugs are present, roosting and nesting sites should be the primary focus, and the animals should be removed and excluded from the building. 
Apply residual Bed Bug Insecticide Spray. After every crack, crevice, switch plate, electrical switch, baseboard, box springs, mattress, etc, has been treated and everything is put back, it is time for the residual treatment. Using a hand held sprayer such as the Chapin Sure Spray apply Optimate, Cy-Kick, Suspend SC or Demand along the baseboards in the bedroom and closet, under and around the bed, behind the headboard, inside bed stands etc.
Prior to the widespread use of synthetic insecticides, this small, brown blood-sucking bug was perhaps the most unwanted pest in America. The insidious bed bug was loathed even more than the cockroach. Although the bug’s impact was greatly reduced by insecticides during the 1940s and 1950s, it remained an occasional invader of homes, hotels and shelters. Pest management professionals now agree that bed bugs have become the most difficult pest to control.
You must repeat the entirety of Step 2 (except for the mattress and box spring treatment if you are encasing) every 7-10 days until no one in the home has bed bug bites and there is no further evidence (live bugs, cast skins, or fresh blood spots) found. This is absolutely crucial! Depending on the severity of the infestation it can take a minimum of 7-8 weeks, including repeat treatments. Failure to be thorough can prolong the process of getting rid of bed bugs and can make it harder to eliminate them.
Another common suggestion is to use either double-sided tape or Vaseline. The theory is that you can stop bed bugs from climbing the legs of your bed by applying these to the legs. Unfortunately, report after report from customers has indicated that these solutions simply don’t work. I hear all the time about bed bugs crawling right over Vaseline, carpet tape, and other adhesive traps like glue boards.

Stripping and vacuuming the mattresses and box springs, and encasing them.  Double bag your bedding and wash in hot water and dry for at least 30 minutes (discard the inner bag after putting bedding into the washer, as it could have bed bugs).  After vacuuming suspected bed bugs from the bed, take your vacuum cleaner outdoors and remove and discard the bag.  Purchase a good quality set of bed-bug-proof encasements for your mattresses and box springs. Bed bug-proof encasements are fabric sacks into which you slide your mattress or your box spring. The zippers on bed bug encasements are designed to be tight enough to prevent even the smallest life stages of the bed bugs from escaping. Also, good bed bug-proof encasements are woven to prevent bed bugs from biting you through the encasement. A good encasement will trap all bed bugs in the mattress and box spring inside, and will be smooth on the outside, providing few places for bed bugs to hide. Sears, Target, Walmart and other stores may sell bed bug-proof encasements, but these can also be purchased online. A good place to look for different brands and reviews of mattress encasements is Amazon.com (whether you buy there or at a local store). Go to http://www.amazon.com and search for “bed bug mattress protectors”.
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