Bag and launder (122°F/50ºC minimum) affected items. Smaller items that cannot be laundered can sometimes be de-infested by heating. Individual items, for example, can be wrapped in plastic and placed in a hot, sunny location for at least a few days (the 122°F/50ºC minimum target temperature should be monitored in the center-most location with a thermometer). Bedbugs also succumb to cold temperatures below freezing, but the chilling period must be maintained for at least two weeks. Attempts to rid an entire home or apartment of bed bugs by raising or lowering the thermostat will be entirely unsuccessful.
After the bugs developed resistance against many of the most powerful pesticides, such as DDT, exterminators had been increasingly relying on two chemicals—chlorfenapyr and bifenthrin. But until now, no one had looked at whether bed bugs were developing defenses against these chemicals too, says Ameya D. Gondhalekar, one of the study authors and a research assistant professor at the Center for Urban and Industrial Pest Management at the Department of Entomology at Purdue University.
Bedbug infestations affect both sexes and people of all ages and races in the United States and globally, particularly in poor regions of the world.  The reported rate of bedbugs (Cimex hemipterus) was 37.5% in children's beds from a rural region of Gambia. Recently, bedbugs were allegedly reintroduced from abroad into Seoul, Korea, because there had been no reports on bedbugs in Seoul for more than 20 years. 
^ Johann Friedrich Wolff; Johann Philip Wolff. "According to Scopoli's 2nd work (loc. cit.), found in Carniola and adjoining regions. According to Linnaeus' second work on exotic insects (loc. cit.), before the era of health, already in Europe, seldom observed in England before 1670". Icones Cimicum descriptionibus illustratae. p. 127. Retrieved 1 December 2016. fourth fascicle (1804)
I paid $1200 for extermination heat treatment- lasted a few months and they are back- bought all new furniture! Still bugs- spray bye bye bugs spray which kills on contact but didn’t stop the infestation! This is going on 2 years now!!!! Mainly they are just in the 2 bedrooms. Ours and one that hardly no one sleeps in. But when grandkids come- they get bitten bad- I scrub, spray, vacuum & steam clean, & wash all bedding n still bit!!! Ready to burn the house down!!! HELP!!!!!! Can’t afford another $1200
In the case of beds, a more economical option is to encase both the mattress and box spring in a protective cover like those used for allergy relief. Encasements specifically designed to help protect against bed bugs are available through retail or pest control firms. Higher quality ones tend to be more durable and comfortable to sleep on. Once the encasement is installed and zipped shut, any bugs which happen to be inside are entombed and eventually will die. Encasements also help protect newly purchased beds, and make it easier to spot and destroy any bugs residing on the outer surface during subsequent examination. Encasements will not, however, keep bed bugs from crawling onto a bed and biting a sleeping person.
With the bed now fully isolated and elevated, bed bugs hiding elsewhere in the room won’t be able to feed on you or hide in your bed. You can also use the ClimbUps to monitor the changing population of bed bugs in your home. Hopefully, you will see less and less bugs appear in the traps as you go through the next steps. Now that you have created a safe haven in your bed, you can move on to treating the rest of the room.
First up is the most commonly recommended tool by far: rubbing alcohol diluted in water. This is suggested because alcohol can kill bed bugs on contact, and evaporates shortly after, so it’s considered safe for use pretty much anywhere in a home. A recurring theme in these recommendations are household items that are considered to be safer for people than mainstream chemicals.
Skin reactions from bed bug bites vary from person to person. Bites may go unnoticed or may be mistaken for flea or mosquito bites or other skin conditions. The most common skin reaction to bed bug bites are itchy red bite marks that appear clustered or in a straight line, often along the edge of clothing or where sheets were pulled up to a person's skin. Small swollen red bumps are also common. In rare cases, people may develop large, often itchy, red welts. A single bed bug bite is similar to a flea bite, except that a red area does not occur in the center. Flea bites tend to be found around the ankles while bed bugs tend to bite any exposed area of the body while a person is sleeping, such as the face, neck, arms, hands, or legs.
Today, bedbugs can be found in every State in the United States, and almost every city. Bedbugs are so common now that the federal government considers them almost "epidemic". The National Pest Management Association has declared war on bed bugs and has held bedbug meetings all across the Nation to help educate pest control companies in an effort to help control them.
Reactions to bed bug bites vary among individuals. Many persons show no signs of bites. Others don’t realize they’ve been bitten until redness and swelling appear around the bite, sometimes with intense itching. Some exhibit inflamed swollen spots that may occur in linear series or have a rash-like appearance. Such bite marks, when they appear, may not show for several days after the person is bitten.
If you arrive home and discover that you have brought some unwanted guests home with you, immediately notify the hotel of your discovery. Having a possible infestation in hotels and motels can be a public relations nightmare for the owners. Politely ask them to pay for any and all costs incurred to rid your clothing and home of a possible new infestation.