Once a pest of the past, bedbugs now infest every state in the U.S.. Cimex lectularius—small, flattened insects that feed solely on mammalian and avian blood—have been living with humans since ancient times. Abundant in the U.S. prior to World War II, bedbugs all but vanished during the 1940s and '50s thanks to improvements in hygiene and the use of pesticides. In the past 10 years, however, the pests have staged a comeback worldwide—an outbreak after the 2000 Summer Olympics in Sydney was a harbinger of things to come. This revival may be the worst yet, experts say, due to densely populated urban areas, global travel and increasing pesticide resistance—something to consider as the summer travel season gets underway.
Both of these types of Hemiptera are sensitive to extreme temperatures. It may be necessary to rid the infestation by exposing the area to extreme heat or cold; they are most comfortable in temperatures around eighty degrees Fahrenheit. Raising the temperature to ninety-seven to ninety-nine degrees may kill off a significant portion of the population.
Items that cannot be placed in a washer or dryer can sometimes be de-infested by wrapping them in plastic and placing them outdoors in a hot, sunny location for at least a day (for example, on pavement or in a closed vehicle parked in the sun). Packing items loosely in garbage bags and elevating objects off the ground helps the heat permeate further, and will make it harder for bugs to find a cool place to hide. Monitoring with a thermometer is prudent to ensure that a temperature of at least 120°F is achieved wherever the bugs may be. 
According to a study carried out on Ortho Home Defense, it contains a chemical bifenthrin that is considered relatively safe and kills off bugs that pyrethroid-based insecticides can’t. It is also effective against bed bug eggs and larvae.12 It should be sprayed as a spot treatment in any crevice where bed bugs can reside. You can get more information about Ortho Home Defense bed bug spray and purchase it in Amazon here.

Bag and launder (122°F/50ºC minimum) affected items. Smaller items that cannot be laundered can sometimes be de-infested by heating. Individual items, for example, can be wrapped in plastic and placed in a hot, sunny location for at least a few days (the 122°F/50ºC minimum target temperature should be monitored in the center-most location with a thermometer). Bedbugs also succumb to cold temperatures below freezing, but the chilling period must be maintained for at least two weeks. Attempts to rid an entire home or apartment of bed bugs by raising or lowering the thermostat will be entirely unsuccessful.[12]

A variety of low-odor sprays, dusts, and aerosol insecticides help with bed bug control. People must apply these pesticides to all areas where the bugs are observed as well as hiding places or spaces where they may crawl. The pest control company can help you determine if an infested mattress can be disinfected or must be discarded. Since beds cannot readily be treated with insecticides, it's often necessary to discard infested mattresses and beds.
Now that you’ve killed the bed bugs hiding in your bed, it’s time to put up defensive measures to keep them out. Remember, bed bugs can be hiding in all sorts of cracks and crevices throughout your bedroom – in furniture, along baseboards, and inside of the walls – so you need a way to keep them out of your freshly treated bed. By cutting off the infestation’s food supply (you), you halt their breeding and reproductive cycle, making the treatment a whole lot easier.
Inspection requires knowledge, dedication and time. At minimum an inspection should involve a detailed examination of mattresses, box springs and bed frames, as well as likely hiding places for bed bugs within 20 feet of beds and other places where residents may sleep or rest, e.g., on couches). Clutter-free space will be needed to allow furnishings to be moved and manipulated for inspection. In general, rooms with more furnishings will take more time to inspect.

To use sprays effectively to eliminate all traces of bed bugs, you need to know the signs of a bed bug infestation. The first sign that you may have bedbugs are some itchy bite marks on your skin when you wake up in the morning. Dr. Carol DerSarkissian on WebMD says that the bites from bed bugs cause red itchy bumps on the skin.3 You can learn about their other signs and symptoms in my articles on what do bed bug bites look like.
Bedbugs are found all over the world. Bed bug infestations were common in the U.S. before World War II and became rare after widespread use of the insecticide DDT for pest control began in the 1940s and 1950s. They remained prevalent in other areas of the world and, in recent years, have been increasingly observed again in the U.S. Increases in immigration and travel from the developing world as well as restrictions on the use of stronger pesticides may be factors that have led to the relatively recent increase in bedbug infestations. While bedbug infestations are often reported to be found when sanitation conditions are poor or when birds or mammals (particularly bats) are nesting on or near a home, bedbugs can also live and thrive in clean environments. Crowded living quarters also facilitate the spread of bedbug infestations.
Most of the time you won't go to a doctor for bedbug bites. But the bites can mimic other rashes or you might have developed a skin infection from scratching. Be prepared with a timeline of your symptoms. You should note any travel you have done, any new furniture, bedding, or mattresses, and a list of your medications and supplements. Bring photos of any suspicious specks found on your bedding or furniture.
According to the Texas A&M University, there are no “magic” insecticide sprays for bed bugs. However, both natural and chemical sprays have a measure of effectiveness against bed bugs. One of the benefits of chemical sprays is that they are stronger and will kill off bed bugs quicker. However, the drawback is that many populations of bedbugs have become resistant to pyrethrins and pyrethroids – the 2 main chemicals in many chemical bed bug sprays. Therefore, they may not be effective in reducing many bed bug populations.5
^ John Southall. "That soon after the Fire of London, in some of the new-built Houses they were observ'd to appear, and were never noted to have been seen in the old, tho' they were then so few, as to be little taken notice of; yet as they were only seen in Firr-Timber, 'twas conjectured they were then first brought to England in them; of which most of the new Houses were partly built, instead of the good Oak destroy'd in the old". A Treatise of Buggs [sic], pp. 16–17. Retrieved 1 December 2016.
Once Step 2B is complete and the insecticide mixture is dry, you can follow up with a bed bug aerosol spray. Bed bug aerosol sprays are insecticides that have fine particles that get deep into cracks and crevices. By using both a liquid concentrate insecticide mixture and an aerosol spray, you can treat bed bugs that may have built up a resistance to one product but not the other.
Bedbugs do, however, have a unique bite pattern. Although some bites may appear alone, most bites occur in a row of three to five bites (termed "breakfast, lunch, and dinner") or in a cluster of red bumps (a rash called bedbug dermatitis). The bites often appear in a zig-zag formation, but may appear in a straight line if the bugs bite you in the morning. 

Some pest control firms also employ commercial steamers or spot-freezing equipment to treat areas where bed bugs are found or suspected. Used correctly, they kill bugs and eggs on contact. Neither method, however, affords residual protection against bed bugs which may have been missed. Steaming and spot-freezing equipment also have limited ability to penetrate fabric, wood, and other materials where bed bugs often reside. 
As per mentioned, when you shift your furniture to located these bed bugs, you alert them and they may move from one infested room to another, which could be spared from in the first place. Therefore, when you spot signs of bed bugs early, be careful not to shift furniture, drawers and closets around too much. Wait for your pest control expert to advice.
Prior to the widespread use of synthetic insecticides, this small, brown blood-sucking bug was perhaps the most unwanted pest in America. The insidious bed bug was loathed even more than the cockroach. Although the bug’s impact was greatly reduced by insecticides during the 1940s and 1950s, it remained an occasional invader of homes, hotels and shelters. Pest management professionals now agree that bed bugs have become the most difficult pest to control.
Bedbug infestations affect both sexes and people of all ages and races in the United States and globally, particularly in poor regions of the world. [12] The reported rate of bedbugs (Cimex hemipterus) was 37.5% in children's beds from a rural region of Gambia. Recently, bedbugs were allegedly reintroduced from abroad into Seoul, Korea, because there had been no reports on bedbugs in Seoul for more than 20 years. [13]
Bed bug bites usually do not pose a serious medical threat. The best way to treat a bite is to avoid scratching the area and apply antiseptic creams or lotions and take an antihistamine. Bed bug infestations are commonly treated by insecticide spraying. If you suspect that you have an infestation, contact your landlord or professional pest control company that is experienced with treating bed bugs. The best way to prevent bed bugs is regular inspection for the signs of an infestation.
^ Kambu, Kabangu; Di Phanzu, N.; Coune, Claude; Wauters, Jean-Noël; Angenot, Luc (1982). "Contribution à l'étude des propriétés insecticides et chimiques d'Eucalyptus saligna du Zaïre (Contribution to the study of insecticide and chemical properties of Eucalyptus saligna from Zaire ( Congo))". Plantes Médicinales et Phytothérapie. 16 (1): 34–38. hdl:2268/14438.
Waking up with bites might be the first indicator that you have a bed bug problem. Their bites are often arranged in lines or clusters on the face, neck, arms or hands. Where there are bed bugs in large numbers, you might smell a sweet, musty odor (from the bugs’ scent glands) or see rust-colored spots on your bedding or mattress caused by bed bug blood or excrement. If you look closely, you might see adult bed bugs themselves, usually in mattress folds or seams or on the wall behind the headboard. Bed bugs prefer to stay close to their food source and are typically found hiding out within 1 to 5 ft of infested beds or furniture.
Track your success. Interceptor cups under your bed posts are also one of the best ways of keeping track of your success with bed bug control. Check the cups regularly and empty into a trash bag or bucket of soapy water.  You may even want to keep track of how many bed bugs you catch weekly so that you can track your success. Wipe out the interceptors and make sure they are clean. Some devices, like the Climbup Interceptor, require redusting with a very small amount of talcum powder to make them slippery again and reduce the bed bug’s chance of escape. Note that talc is not toxic to bed bugs, but simply makes it harder for them to climb out of the cup.  The talc should be barely visible, and more is definitely not better.
Systematically examine and treat all furniture (beds, bed frames, dressers, chairs, couches, night stands, etc.) following the same procedures and recommendations above. As a piece is treated it can be returned to the parts of the room that have been treated.  Note that furniture should be taken apart, drawers and cushions removed in order to inspect and treat every nook and cranny. When treating upholstered furniture, pay attention to each welt, button and fold. You may wish to discard low-value, stuffed furniture that is infested and too difficult to treat.  After spraying, return each article of furniture to the part of the room that has been treated. Do not reintroduce any furniture or other items to the treated room until they have been thoroughly cleaned, inspected or treated.
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