We are often asked, "How do you kill bed bugs?" While we would love to give a simple answer, this is actually a loaded question. There are many ways to kill a bed bug but, if you want to kill all of the bed bugs in your home or business, it is important to pay attention to the details. Here are some ways you can kill bed bugs, and what you should know about each.
Bedbug infestations affect both sexes and people of all ages and races in the United States and globally, particularly in poor regions of the world.  The reported rate of bedbugs (Cimex hemipterus) was 37.5% in children's beds from a rural region of Gambia. Recently, bedbugs were allegedly reintroduced from abroad into Seoul, Korea, because there had been no reports on bedbugs in Seoul for more than 20 years. 
Most bed bug bites go away by themselves and don't need treatment. Keep the skin clean and try not to scratch. Over-the-counter, anti-itching cream for insect bites can help relieve the itching. If the bites are very itchy, your health care provider may prescribe cream or antihistamines to relieve the itchiness. Oral antibiotics may be prescribed for any secondary skin infection from excessive scratching.
Some people develop allergic reactions to bedbug bites, which can include a fever, difficulty breathing, hives, or a swollen tongue. Others may develop an infection where the bite starts oozing pus. If you experience either of these reactions or you develop blisters where the bites occurred, it’s a good idea to make an appointment with a dermatologist.
If you think that by discarding the whole bed means getting rid of bed bugs, you are wrong. By moving the mattress and the bed frame, you not only risk moving the bed bugs all around the house, you are also missing out on many other spots these bed bugs could be at. For example, curtains, floor panels and skirting or even the door frames are able to hide these bed bugs very well. The root causes of the infestation must be eradicated fully.
It is hard to tell if you’ve been bitten by a bed bug unless you find bed bugs or signs of infestation. When bed bugs bite, they inject an anesthetic and an anticoagulant that prevents a person from realizing they are being bitten. Most people do not realize they have been bitten until bite marks appear anywhere from one to several days after the initial bite. The bite marks are similar to that of a mosquito or a flea — a slightly swollen and red area that may itch and be irritating. The bite marks may be random or appear in a straight line. Other symptoms of bed bug bites include insomnia, anxiety, and skin problems that arise from profuse scratching of the bites.
Turns out, C. lectularius is also forming a resistance to other insecticides, according to a study published online April 10, 2017, in the Journal of Economic Entomology. The researchers, from Purdue University, found that three out of 10 bedbug populations collected in the field showed much less susceptibility to chlorfenapyr, and five of the 10 populations showed reduced susceptibility to bifenthrin, according to a post on Entomology Today. The scientists defined "reduced susceptibility" as a population in which more than 25 percent of the begbugs survived after seven days of exposure to the particular insecticide.
Some people have no reaction whatsoever to bed bugs. In addition to not having much of an effect on the elderly, some are just not allergic. Since the irritation and welting appears as the result of an allergic reaction, it is possible to not even know that you were bitten at all. It is entirely possible for several people to live in the same house, and have one person not be affected.
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Thus, although these insects usually cause mild cutaneous reactions, more severe responses, including anaphylaxis, may occur.  Bullae may be noted. Skin responses at bite sites may evolve from immediate, pruritic, edematous macules into bullae within 24 hours. Histopathologically, an urticarial-like reaction can develop into a leukocytoclastic vasculitis, sometimes with a destructive, necrotizing, eosinophil-rich vasculitis with prominent infiltration of CD68+ histiocytes and collagen necrobiosis.
To get rid of bed bugs in a mattress, use an aerosol spray labeled for bed bug treatment, such as Bedlam Aerosol Spray, and spray or mist the insecticide onto the mattress. Focus on the seams, tufts, and folds of the mattress and spray until the mattress is damp. Allow mattress to dry before remaking the bed with freshly laundered sheets that have been run through a dryer on high heat.
Because bed bug bites affect everyone differently, some people may have no reaction and will not develop bite marks or any other visible signs of being bitten. Other people may be allergic to the bed bugs and can react adversely to the bites. These allergic symptoms can include enlarged bite marks, painful swellings at the bite site, and, on rare occasions, anaphylaxis.
One of the easiest ways to identify a bed bug infestation is by the tell-tale bite marks on the face, neck, arms, hands, or any other body parts while sleeping. However, these bite marks may take as long as 14 days to develop in some people so it is important to look for other clues when determining if bed bugs have infested an area. These signs include:
Bed Bugs can re-infest your freshly treated bed, so be sure to stop them from crawling up the bed posts by using Climb-Up Bed Bug Insect Interceptors. The Climb-Up Insect Interceptor is a small dish that is placed under the bed post and captures bedbugs in a a powder coated ring. These type of bed bug traps are very effective and should be used on every bed to help make a complete bed bug proof bed.
Monitor Bed Bug movement with Traps. Bed Bug traps don't work to control bed bugs - they only monitor bed bug movement. Try using Catchmaster 288i Professional Bug Traps by placing them against walls, behind furniture, sticking them under bedframes (yes they work upside down), and anywhere you think bed bugs could be crawling to get back to the bed. Inspect these traps every few days. If you capture bed bugs, then you may have to retreat and do this entire procedure over again. If the traps are empty, then pat yourself on the back for a job well done, but don't think that bed bugs are gone forever. They could be walking around the trap or just waiting for the comforter to hit floor before they climb back into bed!
Symptoms may not appear until some days after the bites have occurred. Reactions often become more brisk after multiple bites due to possible sensitization to the salivary proteins of the bed bug. The skin reaction usually occurs in the area of the bite which is most commonly the arms, shoulders and legs as they are more frequently exposed at night. Numerous bites may lead to an erythematous rash or urticaria.
After bedbugs find a food source, they bite down with their mouths and inject anticoagulant and anesthetic compounds into the skin. Depending on the species, these parasites feed on the host blood via 1 of 2 mechanisms. Vessel feeders directly insert their mouthparts into superficial capillaries, whereas pool feeders damage the superficial tissue and feed on the accumulated blood. As bedbugs feed, their color may change as they swell with the host blood, as shown in this picture of a larval bedbug feeding on a volunteer host. Image courtesy of the US Centers for Disease Control and Prevention (CDC).
It is also recommended to put infested items, such as a mattress, in a sauna that reaches temperatures of upwards of 170° Fahrenheit. Similarly, they also perish in extremely cold temperatures so mattresses and other items can be cleansed of these bugs with the use of plastic wrap and dry ice. Cover the items with large plastic tarps and carefully insert dry ice, and then secure. The extreme temperature will naturally fumigate the pests.
Killing all bed bugs on your bed frame and headboard. Normally this would be done by a pest control professional. Approximately 70% of all bed bugs in the typical infestation are located on the mattress, box spring and bed frame. You’ve encased the mattress and box spring and taken care of that problem. Now you have to make sure that your bed frame is bed bug free. Vacuuming alone won’t do this. Vacuuming can remove many bed bug adults and nymphs, but it isn’t very good at removing eggs. For this job you’ll need insecticide sprays and possibly dusts to treat every crevice and void in your bed. For insecticide spray and dust options see below. Remember that insecticides can be hazardous if you don’t follow label directions. Read the whole label before spraying or dusting. The label directions are the law and failure to follow the label not only puts you and your family at risk, it is against the law. Homemade sprays, by the way, are usually less safe than commercial insecticides. Stick with the legal stuff.
I dont know if my post was received. I am using a phone its started acting weird and my comment was gone. My problem with bedbugs is so horrible I am trying again. I am 60 years old. I have never seen or even heard of someone having these creatures from hell.I am allergic to the bites. The red blotches quickly turned to deep red pus filled holes . Some arw very painful. I feel like my clothes have stickers in them. None of tje high priced insecticides for bedo bugs have did anything. I am actually losing it. I have used a lot of different chemicals because I am so terrible infected by their bite. I have not put a dent in the problem. I think I have poisoned myself. I have holed up in my bedroom embarassed of the bugs and the bjtes that cover my arms, legs back and toros. My son came by and I quickly rushed him outside. Completely puzzled he asked what’s is going on here ? I felt like the most horrible person. I just didnt want him to carry this curse home. I and in a hopess situation.
People don't often consider bed bugs until they've left their mark. The appearance of flat, red welts in zigzag lines or small clusters is a key sign of bed bugs on humans. Bed bugs can also leave their bites in straight rows and, while they don't spread diseases to humans, their bites are quite irritating and scratching them can lead to bleeding and infection.