Turns out, C. lectularius is also forming a resistance to other insecticides, according to a study published online April 10, 2017, in the Journal of Economic Entomology. The researchers, from Purdue University, found that three out of 10 bedbug populations collected in the field showed much less susceptibility to chlorfenapyr, and five of the 10 populations showed reduced susceptibility to bifenthrin, according to a post on Entomology Today. The scientists defined "reduced susceptibility" as a population in which more than 25 percent of the begbugs survived after seven days of exposure to the particular insecticide.
Use of Organic-Based Bed Bug Spray – thanks to growing going green trend, there are now bed bug products made with natural ingredients. With them, you could now get rid of the crawlies safely, easily and inexpensively. However, you should take note that this method only works if you have the best-selling bed bug spray that kills on contact and is without harsh chemical ingredients.
Stripping and vacuuming the mattresses and box springs, and encasing them.  Double bag your bedding and wash in hot water and dry for at least 30 minutes (discard the inner bag after putting bedding into the washer, as it could have bed bugs).  After vacuuming suspected bed bugs from the bed, take your vacuum cleaner outdoors and remove and discard the bag.  Purchase a good quality set of bed-bug-proof encasements for your mattresses and box springs. Bed bug-proof encasements are fabric sacks into which you slide your mattress or your box spring. The zippers on bed bug encasements are designed to be tight enough to prevent even the smallest life stages of the bed bugs from escaping. Also, good bed bug-proof encasements are woven to prevent bed bugs from biting you through the encasement. A good encasement will trap all bed bugs in the mattress and box spring inside, and will be smooth on the outside, providing few places for bed bugs to hide. Sears, Target, Walmart and other stores may sell bed bug-proof encasements, but these can also be purchased online. A good place to look for different brands and reviews of mattress encasements is Amazon.com (whether you buy there or at a local store). Go to http://www.amazon.com and search for “bed bug mattress protectors”.
Apply as a coarse, low-pressure spray to harborage areas including crevices, baseboards, loose plaster, behind bed frames and headboards, beneath beds and furniture, and to bedsprings and bed frames. After removal of bed linens, apply Transport Mikron to mattress and boxsprings. Apply to tufts, edges, seams and folds (do not spray clothes or bed linens). Your may apply it to furniture, but not to areas where there is direct access to seating or arm placements. Infested bed linens should not be treated, but should be removed, placed in sealed plastic bags, and taken for laundering and drying at high temperatures.
Insecticides might also have their work cut out for them: Entomologists have known that the common bedbug has built up resistance to some typical insecticides such as those containing certain pyrethroid chemicals like deltamethrin, according to Entomology Today. Deltamethrin apparently paralyzes an insect's nervous system, according to Cornell University.
"We originally thought the bedbugs might prefer red because blood is red and that's what they feed on," study co-author Corraine McNeill, an assistant professor of biology at Union College in Lincoln, Nebraska, said in a statement. "However, after doing the study, the main reason we think they preferred red colors is because bedbugs themselves appear red, so they go to these harborages because they want to be with other bedbugs, as they are known to exist in aggregations."
Most of the time you won't go to a doctor for bedbug bites. But the bites can mimic other rashes or you might have developed a skin infection from scratching. Be prepared with a timeline of your symptoms. You should note any travel you have done, any new furniture, bedding, or mattresses, and a list of your medications and supplements. Bring photos of any suspicious specks found on your bedding or furniture.
Dessicants are substances that destroy the bugs’ protective outer coating. Without this coating, the bugs dry out and die. Two examples of dessicants are silica aerogel (Tri-Die and CimeXa) and diatomaceous earth. The advantage to dessicants is that bedbugs can’t become resistant to them, but they work slowly. These products can take a few months to kill off all the bugs.
To begin, strip your bed of all sheets, pillowcases, and other bedding, and seal them in plastic garbage bags to keep bed bugs from escaping and infesting other parts of your home. Take the bags straight to the washing machine, and wash them using the hot water setting. Then, dry the bedding on high heat if their tags allow it. This heat treatment will kill any bed bugs or eggs hiding in your bedding.
Treat or isolate your bagged items. For washable items research shows that dry cleaning, washing in hot water for 30 minutes, or tumble drying for 30 minutes on high will kill all stages of bed bugs. Non-washables items that aren’t needed for a while can just be stored. It takes 2-5 months to kill bed bugs by isolating them in bags or heating bags by placing in direct sunlight is one of the most effective methods during the warm summer months.  
Bed bugs feed exclusively at night. They take approximately three to five minutes to engorge on blood. Once feeding is complete, they return to their harborage. Feedings take place every few days and nymphs require approximately six blood meals for complete development. Humans are the preferred host for the common bed bug, but it will feed readily on other animals, such as poultry, mice, rats, canaries, dogs, and cats, when necessary. Normally the bugs feed at night, but they will feed during daylight hours in places such as theaters, offices, and rest rooms that are not ordinarily used at night.
Perform a quick inspection of the upper piping every time you change your sheets. Make a more thorough examination by folding the piping over and closely inspecting both sides all the way around, top and bottom. Do this a couple times a year or every time you flip or rotate your mattress. If you spot any signs, keep reading to learn how to get rid of bed bugs.
Bring in only what is needed, and avoid sitting or placing coats and other items on beds, floors and sofas where the bugs commonly reside. Essential items can be placed on a tabletop or other hard surface, preferably away from bedrooms and sleeping areas. Better to sit on a hard (non-upholstered) chair than on sofas and recliners. Also try to avoid leaning or brushing against beds and upholstered furniture. If such items are carried out of infested dwellings (e.g., by sanitation workers or firefighters), it’s best to wrap them in plastic or at least not hold them against your body during transport. Emergency Medical (EMS) personnel may need to take additional precautions, such as removing a patient’s bed bug-infested shoes or clothing, or installing plastic sheeting before transporting them in the emergency vehicle.    

While alcohol can kill bed bugs on contact, it’s not going to kill nearly enough of bed bugs to be considered effective. In lab studies, even 99 percent concentrations of alcohol only killed between 40% to 60% of the adults that were sprayed. On top of that, alcohol has no long-lasting residual effect, and doesn’t affect bed bug eggs. 60% sounds good, but a contact killer should be able to kill a lot closer to 100% of the bed bugs you see. Otherwise, a shoe or a blowtorch would be the more reliable tool for the job. (Editor’s note: please don’t use a blowtorch.)
Visit your doctor. You can also see a doctor for diagnosis if you do not find signs of bedbugs in your bed and cannot identify the source of the bites or rash. However, there is a very good chance that your physician will not be able to firmly diagnose that you have been bitten by a bedbug because the symptoms look so similar to those that result from other insect bites and skin conditions. Nevertheless, you may feel comforted by going to see your doctor, who can confirm for you that bedbugs pose little physical threat to humans.
Pesticides alone are not the answer to bed bugs. Most of the commonly used pesticides today, including professional products and consumer products advertised for control of bed bugs, are at best moderately effective at controlling these pests. Pesticides must be used with care for safety and with attention to proper application to work well. Aerosol “bug bombs” or “fumigators” are also mostly ineffective in eliminating bed bugs. Aerosol insecticides mainly kill insects that are exposed, and out of their hiding places, not those hidden behind baseboards, in cracks and crevices of the bed, under carpet edging and in walls.
Bring in only what is needed, and avoid sitting or placing coats and other items on beds, floors and sofas where the bugs commonly reside. Essential items can be placed on a tabletop or other hard surface, preferably away from bedrooms and sleeping areas. Better to sit on a hard (non-upholstered) chair than on sofas and recliners. Also try to avoid leaning or brushing against beds and upholstered furniture. If such items are carried out of infested dwellings (e.g., by sanitation workers or firefighters), it’s best to wrap them in plastic or at least not hold them against your body during transport. Emergency Medical (EMS) personnel may need to take additional precautions, such as removing a patient’s bed bug-infested shoes or clothing, or installing plastic sheeting before transporting them in the emergency vehicle.     
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