Bedbug bites themselves are typically painless. However, the subsequent allergic reaction that may develop can cause intense pruritus. While feeding, bedbugs may inject one of several pharmacologically active substances, including hyaluronidase, proteases, and kinins. These compounds may induce different skin reactions, such as erythema, wheals, vesicles, or hemorrhagic nodules. Repeated bites may sensitize individuals, leading to more pronounced cutaneous manifestations or systemic hypersensitivity reactions. The local trauma from bedbug bites can lead to secondary bacterial infection, causing ecthyma, cellulitis, or lymphangitis. There is some evidence that bedbugs may also be a vector for hepatitis B and Chagas disease. Histologic findings from bite-site biopsy specimens typically show eosinophilic infiltrates, which are indicative of the allergic nature of the reaction. The image shown is papular urticaria, which may develop from bedbug bites.
Bedbugs are small oval-shaped non-flying insects that belong to the insect family Cimicidae, which includes three species that bite people. Adult bedbugs reach 5 mm-7 mm in length, while nymphs (juveniles) are as small as 1.5 mm. Bedbugs have flat bodies and may sometimes be mistaken for ticks or small cockroaches. Bedbugs feed by sucking blood from humans or animals. Cimex lectularius is the scientific name for bedbugs.
Fumigation using a penetrating gas is another way to de-infest dwellings or furnishings, but the procedure is only offered by certain companies. True fumigation is not the same as setting off a total release fogger or ‘bug bomb.’ (It should be noted that bug bombs are considered ineffective in the treatment of bed bugs, and can be quite dangerous if misused.) The fumigation process is technically complex and requires vacating the building for a period of days. The building is then sealed and injected with a lethal gas, usually sulfuryl fluoride. Because the entire building must be vacated, structural fumigation is logistically more challenging with multi-unit buildings such as apartments, than for single family homes. Bed bug fumigations tend to be more common in southern and western states, where the procedure is also used to control certain types of wood-dwelling termites.  
Bed bugs are troublesome household pests. They’re sneaky, hard to find, and can pose potential health risks for you and your family. Armed with pest control capabilities backed by science, over 100 years of experience, and state-of-the-art tools and products, Orkin is well-equipped to assess your bed bug problem and mount a strategic response to rid your home of the pest and provide maximum protection.

Bed bugs are tiny, flat, wingless insects that range in color from nearly white to deep brown/reddish. The parasitic pests get their name from their hiding spot of choice – they prefer burrowing into bed frames and mattresses during the day, then become active at night when they feed on people and pets. Bed bugs are resilient pests that can hitch a ride on luggage, furniture, storage boxes, backpacks and clothing (but rarely humans), very quickly causing an infestation.
Units that produce “dry” steam are less likely to damage household goods. Steam must be at least 113 degrees Fahrenheit (F), the minimum temperature to kill bed bugs, and care must be taken to reduce pressure so that bed bugs are not literally “blown away” before they can be killed by the steam. Steaming should be avoided around hazards such as electrical outlets.
Start with the bed, including mattress, box-spring and bed frame. Inspect the visible areas first. Look along all edges and corners.  Also check along all stitch lines and the mattress label. Five sides the mattress can be checked while the mattress is on the bed.  When you are finished checking the upper surfaces, you can then stand the mattress upright so you can check the bottom of the mattress.
Bed bug bites are caused primarily by two species of the insect Cimex: Cimex lectularius (the common bed bug) and Cimex hemipterus.[3] Their size ranges between 1 and 7 mm.[7] They spread by crawling between nearby locations or by being carried within personal items.[2] Infestation is rarely due to a lack of hygiene but is more common in high-density areas.[8][2] Diagnosis involves both finding the bugs and the occurrence of compatible symptoms.[5] Bed bugs spend much of their time in dark, hidden locations like mattress seams or cracks in the wall.[2]
Bed bugs are very hardy insects. Both adults and nymphs can survive prolonged periods without food or under adverse temperature conditions. Adults can live for a year or longer without feeding and can survive over winter in an unheated building. Nymphs are not as hardy as adults, but they can survive for considerable periods under adverse conditions.
Skin reactions from bed bug bites vary from person to person. Bites may go unnoticed or may be mistaken for flea or mosquito bites or other skin conditions. The most common skin reaction to bed bug bites are itchy red bite marks that appear clustered or in a straight line, often along the edge of clothing or where sheets were pulled up to a person's skin. Small swollen red bumps are also common. In rare cases, people may develop large, often itchy, red welts. A single bed bug bite is similar to a flea bite, except that a red area does not occur in the center. Flea bites tend to be found around the ankles while bed bugs tend to bite any exposed area of the body while a person is sleeping, such as the face, neck, arms, hands, or legs.
Bedbugs are highly resistant to many sprays. There are, however, certain sprays that may be able to kill bedbugs. Check with a professional exterminator about advice using sprays to try and remove the bedbugs yourself. Dead bedbugs usually won't move, may be arched back, or red in color. Ultimately, you may be better off replacing your mattress and bedding and fumigating your home to kill the bedbugs.
When people are bitten, they often do not notice at first. It’s a possibility that one reason could be that these blood sucking insects feed late in the night, before the breaking of dawn. Humans are often in a deep REM sleep during that time. Upon arising, individuals can find bite marks; however it can take up to ten days for adverse or allergic reactions to develop.
A bedbug will pierce the skin of its host with its mouth part. It first injects saliva that is a mixture of an anesthetic, so that the host feels nothing, and an anticoagulant so that the blood flows out freely. It then sucks out blood until it is full. The bites are not noticeable until after the skin reaction has occurred. According to the Centers for Disease Control and Prevention (CDC), it can take up to 14 days for bites to appear.
Vacuum your house. This will remove bugs and eggs from mattresses, carpet, walls and other surfaces. Pay particular attention to seams, tufts and edges of mattresses and box springs, and the perimeter edge of wall-to-wall carpets. Afterward, dispose of the vacuum contents in a sealed trash bag. Steam cleaning of carpets is also helpful for killing bugs and eggs that vacuuming may have missed.[14]

Dessicants are substances that destroy the bugs’ protective outer coating. Without this coating, the bugs dry out and die. Two examples of dessicants are silica aerogel (Tri-Die and CimeXa) and diatomaceous earth. The advantage to dessicants is that bedbugs can’t become resistant to them, but they work slowly. These products can take a few months to kill off all the bugs.
Heat Treatment – this method kills bed bugs with heat. This could be implemented on clothes by putting them in a drier at a high temperature for 30 minutes. In a room, the use of heating devices could kill even the eggs and the nymphs of bed bugs at certain levels temperature at different durations of time. Ideally, to kill bed bugs in all stages, the temperature must be 115 degrees F or 46 degrees C.
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