Killing all bed bugs on your bed frame and headboard. Normally this would be done by a pest control professional. Approximately 70% of all bed bugs in the typical infestation are located on the mattress, box spring and bed frame.  You’ve encased the mattress and box spring and taken care of that problem.  Now you have to make sure that your bed frame is bed bug free. Vacuuming alone won’t do this.  Vacuuming can remove many bed bug adults and nymphs, but it isn’t very good at removing eggs.  For this job you’ll need insecticide sprays and possibly dusts to treat every crevice and void in your bed.  For insecticide spray and dust options see below. Remember that insecticides can be hazardous if you don’t follow label directions.  Read the whole label before spraying or dusting.  The label directions are the law and failure to follow the label not only puts you and your family at risk, it is against the law.  Homemade sprays, by the way, are usually less safe than commercial insecticides.  Stick with the legal stuff.

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We recommend spraying Steri-Fab in areas where live bed bugs are visible. Steri-Fab combines a synthetic pyrethroid insecticide and isopropyl alcohol to kill bed bugs fast on contact. Steri-Fab also acts as a sanitizer. Steri-Fab does not leave any residual, meaning it can be applied virtually anywhere. Simply shake well, then apply to desired treatment areas. Insect mortality is imminent, generally within 10 minutes of spraying.
Bed bug bites usually do not pose a serious medical threat. The best way to treat a bite is to avoid scratching the area and apply antiseptic creams or lotions and take an antihistamine. Bed bug infestations are commonly treated by insecticide spraying. If you suspect that you have an infestation, contact your landlord or professional pest control company that is experienced with treating bed bugs. The best way to prevent bed bugs is regular inspection for the signs of an infestation.
When the controversial pesticide DDT was banned in 1972, most bed bugs were already resistant to it, Schal says, and today's populations are even more widely resistant thanks to the use of a new class of pesticides. Pyrethroids, the main class of pesticides used against bedbugs today, targets sodium channels in bedbug cells, just like DDT. Consequently, as bedbugs develop resistance to pyrethroids, they also become cross-resistant to DDT.
Flat surfaces can be wiped with alcohol or sprayed with a bed bug—killing contact pesticide, but all items that have a small nook or cranny where bed bugs could hide (which is most stuff) need to be treated with penetrating fumes. Build yourself a kill chamber out of a large storage bin. Tape a pesticide strip to the side or lid of the bin, and seal your stuff inside for a couple days or however long the manufacturer recommends. Seal the lid of the bin with duct tape.
First up are the contact sprays, like STERI-FAB and JT Eaton Kills Bed Bugs. These will kill quickly, but evaporate shortly after, leaving no long-lasting protection. Spray along baseboards, below drawers and on drawer slides, behind cabinets, and behind night stands. Follow up with a residual spray, such as Bedlam Plus and JT Eaton Kills Bed Bugs Plus. Residual sprays will offer long-lasting protection against bed bugs and hatchlings. Bedlam Plus is ideal for cracks and crevices throughout the room, while JT Eaton Plus can be used below the cushions and bases of sofas, chairs, edges of carpets and other fabric items.
Are there pesticides that kill bed bugs? Yup. There sure are. Pest control companies often use pesticides to exterminate these bugs as part of a heat treatment, and also by themselves. But chemicals have some drawbacks that pest professionals are aware of. These products can drive bed bugs into walls, like an improperly applied heat treatment, and they can be ineffectual if bed bugs are deep inside furniture. There are also safety considerations that need to be considered when applying any pesticide.
Prepare the room by separating treated from untreated furniture.  This will involve moving all your furniture to one side of the infested room (Remember, you’ve already assessed which rooms you think are infested.  You may not need to do this in every room).  The process is important because if you treat half of the items in a room and leave other areas untreated, bed bugs may return to the previously treated areas from untreated sites. Take all clothes from drawers, infested closets, etc. and double bag them in clear plastic bags (clear bags are easier to see where things are). Also double bag all personal items (toys, papers, books, electronics, CDs, or anything that could serve as a hiding place for bed bugs) and set them aside until they can be carefully treated, cleaned or inspected. 

Research has shown that some bed bugs are resistant to the pyrethroid pesticides that have been most commonly used in recent years by pest management professionals. Likewise, pyrethroids such as deltamethrin and permethrin have been among the active ingredients most commonly available in pesticides at retail stores. The ongoing use of pyrethroids has undoubtedly contributed to the resistance we see today in some bed bug populations.


"In the past, bedbugs have repeatedly shown the ability to develop resistance to products overly relied upon for their control. The findings of the current study also show similar trends in regard to chlorfenapyr and bifenthrin resistance development in bedbugs," study researcher Ameya Gondhalekar, research assistant professor at Purdue's Center for Urban and Industrial Pest Management, said in the Entomology Today statement. "With these findings in mind and from an insecticide resistance management perspective, both bifenthrin and chlorfenapyr should be integrated with other methods used for bed bug elimination in order to preserve their efficacy in the long term."


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First up are the contact sprays, like STERI-FAB and JT Eaton Kills Bed Bugs. These will kill quickly, but evaporate shortly after, leaving no long-lasting protection. Spray along baseboards, below drawers and on drawer slides, behind cabinets, and behind night stands. Follow up with a residual spray, such as Bedlam Plus and JT Eaton Kills Bed Bugs Plus. Residual sprays will offer long-lasting protection against bed bugs and hatchlings. Bedlam Plus is ideal for cracks and crevices throughout the room, while JT Eaton Plus can be used below the cushions and bases of sofas, chairs, edges of carpets and other fabric items.

"In the past, bedbugs have repeatedly shown the ability to develop resistance to products overly relied upon for their control. The findings of the current study also show similar trends in regard to chlorfenapyr and bifenthrin resistance development in bedbugs," study researcher Ameya Gondhalekar, research assistant professor at Purdue's Center for Urban and Industrial Pest Management, said in the Entomology Today statement. "With these findings in mind and from an insecticide resistance management perspective, both bifenthrin and chlorfenapyr should be integrated with other methods used for bed bug elimination in order to preserve their efficacy in the long term."


Dismantling bed frames in infested areas typically exposes bed bug hiding sites. Having access to these areas during cleaning is important. Stand up the box spring and shine a flashlight through the gauze fabric and look for bed bugs. If the fabric is torn (possible hiding place), remove fabric to prepare for spraying. If the mattress and or box springs are infested, you may want to consider Encasements by Mattress Safe. Once covered with these encasements, bed bugs can not enter or exit. There is no need to treat the mattress or box spring when using these encasements. Keep them on for a year.
A definitive diagnosis of health effects due to bed bugs requires a search for and finding of the insect in the sleeping environment as symptoms are not sufficiently specific.[5] Bed bugs classically form a line of bites colloquially referred to as "breakfast, lunch, and dinner" and rarely feed in the armpit or behind the knee which may help differentiate it from other biting insects.[4] If the number in a house is large a pungent sweet odor may be described.[4] There are specially trained dogs that can detect this smell.[2]
Some pest control firms also employ commercial steamers or spot-freezing equipment to treat areas where bed bugs are found or suspected. Used correctly, they kill bugs and eggs on contact. Neither method, however, affords residual protection against bed bugs which may have been missed. Steaming and spot-freezing equipment also have limited ability to penetrate fabric, wood, and other materials where bed bugs often reside. 
Dogs have been sniffing out insects such as termites for many years, and are now being used as inspection tools for bed bug detection. But while companies using dogs may advertise them as being highly accurate in finding bed bugs, one should not get the impression that dogs are infallible or that they are in all ways superior to human inspectors. Research on the effectiveness of dogs as bed bug detectors suggests that for those who would employ dogs, the message is buyer beware. There appears to be great variance in the accuracy of bed bug dogs, and even well-trained dogs are subject to missing bed bugs and to giving “false positives” (signaling the presence of bed bugs where there are none).
Dusts have been used to ward off insects from grain storage for centuries, including plant ash, lime, dolomite, certain types of soil, and diatomaceous earth or Kieselguhr.[60] Of these, diatomaceous earth in particular has seen a revival as a nontoxic (when in amorphous form) residual pesticide for bed bug abatement. While diatomaceous earth performed poorly, silica gel may be effective.[61][62]
Bedbugs bite and suck blood from humans. Bedbugs are most active at night and bite any exposed areas of skin while an individual is sleeping. The face, neck, hands, and arms are common sites for bedbug bites. The bite itself is painless and is not noticed. Small, flat, or raised bumps on the skin are the most common sign; redness, swelling, and itching commonly occur. If scratched, the bite areas can become infected. A peculiarity of bedbug bites is the tendency to find several bites lined up in a row. Infectious-disease specialists refer to this series of bites as the "breakfast, lunch, and dinner" sign, signifying the sequential feeding that occurs from site to site. In some people, the bites can take several days to develop. The signs may become apparent up to 14 days after the bite has occurred.
A flashlight:  Bed bugs hide in dark areas and in cracks and crevices.  Bed bugs are a dark red to brown color, but they can be light brown if they haven’t been feeding. This makes it very hard to see them. When hunting for bed bugs hold your flashlight parallel to the surface being inspected, this will cause eggs and small bed bugs to cast a shadow, making them easier to find.
Once the mattress and box spring are dry, encase them in sealed bed bug encasements. Encasements are crucial, as they prevent bed bugs from entering or escaping the mattress and box spring, cutting off key hiding places. Remember to leave the encasements on for at least 18 months to ensure that any bed bugs already inside have starved to death. Once the encasements have been applied, you can put your mattress and box springs back on your treated bed frame, and put your laundered bedding back on your bed.
Oil-based products have been so frequently touted as natural bed bug killers that they’ve even attracted government intervention. The Federal Trade Commission has charged multiple companies with deceptive advertising for overhyping their cedar oil-based products’ ability to treat an infestation. By claiming that their products can stop and prevent bed bug infestations, these marketers opened the door to government lawsuits for misleading their customers.
Symptoms may not appear until some days after the bites have occurred.[5] Reactions often become more brisk after multiple bites due to possible sensitization to the salivary proteins of the bed bug.[3] The skin reaction usually occurs in the area of the bite which is most commonly the arms, shoulders and legs as they are more frequently exposed at night.[5] Numerous bites may lead to an erythematous rash or urticaria.[5]

Oil-based products have been so frequently touted as natural bed bug killers that they’ve even attracted government intervention. The Federal Trade Commission has charged multiple companies with deceptive advertising for overhyping their cedar oil-based products’ ability to treat an infestation. By claiming that their products can stop and prevent bed bug infestations, these marketers opened the door to government lawsuits for misleading their customers.


In the case of beds, a more economical option is to encase both the mattress and box spring in a protective cover like those used for allergy relief. Encasements specifically designed to help protect against bed bugs are available through retail or pest control firms. Higher quality ones tend to be more durable and comfortable to sleep on. Once the encasement is installed and zipped shut, any bugs which happen to be inside are entombed and eventually will die. Encasements also help protect newly purchased beds, and make it easier to spot and destroy any bugs residing on the outer surface during subsequent examination. Encasements will not, however, keep bed bugs from crawling onto a bed and biting a sleeping person.


Bed bug sprays usually act as an insecticide and repellent. The best kind of bed bug sprays should kill bed bugs on contact and need to be used repeatedly to help eliminate your bug problem. According to the Texas A&M University, bed bug sprays are best used in combination with other bug control methods like natural bed bug powders. This is because bed bugs don’t build up resistance to natural bug powders and products like diatomaceous earth which kills bed bugs as long as the powder is dry.5
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