One of the many uses of tea tree oil around the house is to use it as a DIY natural bed bug spray. Tea tree oil contains compounds that have an insecticidal effect against insects as well as their larvae and eggs. Although no direct studies have been published on the effect of tea tree oil on bed bugs, research has shown that it has a lethal effect on many bugs and insects.
Turns out, C. lectularius is also forming a resistance to other insecticides, according to a study published online April 10, 2017, in the Journal of Economic Entomology. The researchers, from Purdue University, found that three out of 10 bedbug populations collected in the field showed much less susceptibility to chlorfenapyr, and five of the 10 populations showed reduced susceptibility to bifenthrin, according to a post on Entomology Today. The scientists defined "reduced susceptibility" as a population in which more than 25 percent of the begbugs survived after seven days of exposure to the particular insecticide.
While the mattress and box spring are left to dry, spray down the joints of the bed frame, headboard, and footboard with a contact spray and residual spray. The contact spray will kill bed bugs quickly and then evaporate, while the residual spray will kill bed bugs over several weeks. Remember to follow the sprays’ product labels and MSDS for safe and effective usage. 

Some firms want beds stripped and furniture moved before they arrive, while other firms prefer to inspect first and perform these tasks themselves. Clutter and belongings on floors (especially beneath beds) must be removed since they impede treatment and afford additional places for bugs to hide. Bedding and garments normally will need to be laundered and/or hot dried (120°F minimum) since they cannot be treated with insecticides. An effective and efficient alternative to laundering is to simply place bedding, clothing, toys, shoes, backpacks, etc., in a clothes dryer set at medium-to-high heat for 10 to 20 minutes. This can be done in lieu of washing and will kill all bed bug life stages. 
Bed bugs feed exclusively at night. They take approximately three to five minutes to engorge on blood. Once feeding is complete, they return to their harborage. Feedings take place every few days and nymphs require approximately six blood meals for complete development. Humans are the preferred host for the common bed bug, but it will feed readily on other animals, such as poultry, mice, rats, canaries, dogs, and cats, when necessary. Normally the bugs feed at night, but they will feed during daylight hours in places such as theaters, offices, and rest rooms that are not ordinarily used at night.
Adult bed bugs are brown, 1/4 to 3/8 inch long, and have a flat, oval-shaped body. Young bed bugs (called nymphs) are smaller and lighter in color. Bed bugs hide in a variety of places around the bed. They might also hide in the seams of chairs and couches, between cushions, and in the folds of curtains. They come out to feed about every five to ten days. But they can survive over a year without feeding.
According to textile experts (Drycleaning & Laundry Institute, Laurel, MD), most garments designated as ‘dry-clean only’ (e.g., cotton, wool, silk, linen, rayon, nylon) will not be harmed provided they are dry before being placed in a clothes dryer at a moderate temperature setting. Dry cleaning procedures also kill bed bugs, but there is a risk of infesting the establishment when buggy items are tagged and sorted. 
Stripping and vacuuming the mattresses and box springs, and encasing them.  Double bag your bedding and wash in hot water and dry for at least 30 minutes (discard the inner bag after putting bedding into the washer, as it could have bed bugs).  After vacuuming suspected bed bugs from the bed, take your vacuum cleaner outdoors and remove and discard the bag.  Purchase a good quality set of bed-bug-proof encasements for your mattresses and box springs. Bed bug-proof encasements are fabric sacks into which you slide your mattress or your box spring. The zippers on bed bug encasements are designed to be tight enough to prevent even the smallest life stages of the bed bugs from escaping. Also, good bed bug-proof encasements are woven to prevent bed bugs from biting you through the encasement. A good encasement will trap all bed bugs in the mattress and box spring inside, and will be smooth on the outside, providing few places for bed bugs to hide. Sears, Target, Walmart and other stores may sell bed bug-proof encasements, but these can also be purchased online. A good place to look for different brands and reviews of mattress encasements is Amazon.com (whether you buy there or at a local store). Go to http://www.amazon.com and search for “bed bug mattress protectors”.
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