While most of the bed bugs were wiped out by the chemicals, three groups continued to thrive after being treated with chlorfenapyr, and five groups were still kicking after being treated with bifenthrin. That means that while some bed bugs will respond to these chemicals, others won't—and it's likely that more and more bugs will become resistant over time.
General housecleaning measures, (e.g. vacuuming floors and surfaces), seldom reach where bed bugs hide. For this reason, repetitive vacuuming by occupants may not be worth the effort, especially compared to other important preparatory activities. Targeted vacuuming of bed bugs and infested harborages, however, can help remove some of the bugs before other treatment measures are undertaken. Bed bugs and especially the eggs can be difficult to dislodge. Optimum results will be achieved by moving and scraping the end of the suction wand along infested areas such as seams and fabric folds of beds and sofas, and the perimeter edge of wall-to-wall carpet. Bed bugs can survive the high speed trip down a vacuum, so it’s important to carefully dispose of the vacuum contents in a sealed trash bag afterwards. 

Insecticides might also have their work cut out for them: Entomologists have known that the common bedbug has built up resistance to some typical insecticides such as those containing certain pyrethroid chemicals like deltamethrin, according to Entomology Today. Deltamethrin apparently paralyzes an insect's nervous system, according to Cornell University.
Some preparation is still required (e.g. removal of heat-sensitive items such as aerosol cans, indoor plants and medications), but it is seldom necessary to bag, launder and/or hot dry bedding and clothing since these items will be heated along with other furnishings. Another advantage of heat treatment is that infestations can often be eliminated in one day, rather than over multiple days or weeks. Conversely, heat treatment alone has no lasting (residual) effect should bed bugs be reintroduced into the dwelling. Consequently, some companies recommend concurrently applying residual insecticides. To further minimize reintroduction, occupants are advised to take as few belongings as possible with them while the heat treatment is in progress.    
Pest management professionals are increasingly looking to heat to control bed bugs. Whole houses and, in some cases, multi-unit structures are heated to temperatures well above those lethal to bed bugs, to help assure uniform heating of household contents. Rooms must be heated for several hours during which bulky contents are turned to help ensure heat penetration deep enough to kill bed bugs hiding inside.
Alcohol will kill bed bugs but not their eggs and will need to be used often to control infestation. It is not an effective way to get rid of bed bugs permanently. If you want to use this bed bug treatment you need to mix nine parts 91 percent isopropyl (rubbing) alcohol with one part water. Place the solution in a chemical sprayer to cover large areas. Use a spray bottle for small areas and to get into crevices. Spray all areas including head/foot boards, hard surfaces, base boards, door jams and any other bed bug hiding spots.
Traps aren’t an effective way to wipe out a bed bug infestation, but they’re an excellent way to determine whether you have them. Set traps in areas where they may hide or travel, like near baseboard trim or under nightstands. If they aren’t living in your mattress or other parts of your bed, that means they need to travel up the legs of the bed frame to get to you, so place traps there as well.
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After treating a mattress or box spring for bed bugs, we recommend encasing each in a bed bug proof cover. This will prevent re-infestation and will make future inspections and treatments easier. Be sure any product that has been sprayed or applied to your mattress is dry before you cover the mattress with a bed bug proof cover. You can make the bed with your freshly laundered linens over a bed bug proof mattress cover. 

Aerosols (D-Fense NXT, Crossfire Aerosol, or Bedlam Plus) Usage: Simply attach the plastic tip to the aerosol can. Apply as a crack and crevice or spot treatment where evidence of bed bugs occurs. This includes bed frames, box springs, inside empty dressers, clothes closets, curtain rods, hollow spaces, carpet edges, high and low wall moldings and wallpaper edges.
With the bed now fully isolated and elevated, bed bugs hiding elsewhere in the room won’t be able to feed on you or hide in your bed. You can also use the ClimbUps to monitor the changing population of bed bugs in your home. Hopefully, you will see less and less bugs appear in the traps as you go through the next steps. Now that you have created a safe haven in your bed, you can move on to treating the rest of the room.
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