Bed bugs were first mentioned in Germany in the 11th century, in France in the 13th century, and in England in 1583, though they remained rare in England until 1670. Some in the 18th century believed bed bugs had been brought to London with supplies of wood to rebuild the city after the Great Fire of London (1666). Giovanni Antonio Scopoli noted their presence in Carniola (roughly equivalent to present-day Slovenia) in the 18th century.
Bedbug infestations affect both sexes and people of all ages and races in the United States and globally, particularly in poor regions of the world.  The reported rate of bedbugs (Cimex hemipterus) was 37.5% in children's beds from a rural region of Gambia. Recently, bedbugs were allegedly reintroduced from abroad into Seoul, Korea, because there had been no reports on bedbugs in Seoul for more than 20 years. 
Bed bugs are a growing problem in schools and daycares. Typically they are introduced by students or staff living with an infestation at home. Pinpointing where the bugs exist can be challenging in such environments since there are no beds or sleeping areas for the insects to congregate. (Similar challenges occur when bed bugs are found in offices, libraries and retail stores.) Usually only small numbers of bed bugs are spotted, often on a student’s clothing, backpack, chair or desk. While this does not necessarily confirm that the child’s residence also has bed bugs, the parents should be notified that the home should be inspected, preferably by a professional. Teachers, nurses, and staff should be educated about the bugs and what they look like. Bed bugs should also be considered if a student frequently has reddened itchy welts --but keep in mind such reactions can be for reasons other than bed bugs.
We are often asked, "How do you kill bed bugs?" While we would love to give a simple answer, this is actually a loaded question. There are many ways to kill a bed bug but, if you want to kill all of the bed bugs in your home or business, it is important to pay attention to the details. Here are some ways you can kill bed bugs, and what you should know about each.
Successful control of bed bugs often depends on thorough inspection of the premises believed to be infested. Finding no insects identified as bed bugs does not mean that bed bugs are not present. It can mean that the inspection was inadequate, or that bed bugs are present but so few in number that the inspector missed them. It is not uncommon for even the most diligent and experienced inspectors to fail to find all of the bed bugs present in a structure.
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Begin by reducing clutter in the room; things like clothes, books, and other personal belongings shouldn’t be left on the floor, as they make treatment more difficult and add hiding places for bed bugs and eggs. Seal those items in garbage bags and store them away from the room. Any clothing that was picked up or removed from dresser drawers should be dried on high heat for at least 45 minutes. Once treated, clothing that you don’t normally wear should be stored inside garbage bags outside of the infested room.
Insecticide Application This is the most common way to get rid of bedbugs, Lazarus says. Oftentimes, the professional will use several different products to effectively treat the area, though it may take a few rounds to ensure removal. “The advantage to this method is that the residual insecticide will continue to offer protection for a period of time,” Lazarus says. “The biggest drawback is that the preparation for service is time-consuming and must be repeated prior to each service.”
We recommend spraying Steri-Fab in areas where live bed bugs are visible. Steri-Fab combines a synthetic pyrethroid insecticide and isopropyl alcohol to kill bed bugs fast on contact. Steri-Fab also acts as a sanitizer. Steri-Fab does not leave any residual, meaning it can be applied virtually anywhere. Simply shake well, then apply to desired treatment areas. Insect mortality is imminent, generally within 10 minutes of spraying.
Isolating your bed from the rest of the house. If you don’t use a bed, purchase a frame that gets your mattress off the floor and install bed bug interceptors under all feet of the bed frame to keep bed bugs off your bed while you are sleeping. Interceptors are special platforms or cups that are purchased to prevent bed bugs from climbing on to your bed. An interceptor can be as simple as a sticky card placed under a bed post (sticky and messy). Better are one of the commercial pitfall traps made specifically for this purpose. The Climbup™ Bed bug Interceptor and BlackOut BedBug Detector (Google them) are two such products sold online. Relatively inexpensive, these cups trap bed bugs attempting to climb (or exit) the bed. If you have encased your bedding, treated your bed frame thoroughly and installed interceptors, you will be instantly protected against bed bugs. Don’t take out your clean bedding or put it back on the bed until the bed has been treated (and dried) and encasements installed. And note that for this method to be effective, beds and bedding must not touch the floor, furniture or walls. This would provide bed bugs other ways to climb onto the bed and foil your defenses.
To prevent bringing bed bugs to one's own home, travelers are advised to take precautions after visiting an infested site: generally, these include checking shoes on leaving the site, changing clothes in a garage before returning to their home, and putting the used clothes in a clothes dryer outside the house. When visiting a new lodging, it is advised to check the bed before taking suitcases into the sleeping area and putting the suitcase on a raised stand to make bedbugs less able to crawl in. "An extreme measure would be putting the suitcase in the tub." Clothes should be hung up or left in the suitcase, and never left on the floor. The founder of a company dedicated to bedbug extermination said that 5% of hotel rooms he books into were infested. He advised people never to sit down on public transport; check office chairs, plane seats and hotel mattresses, and monitor and vacuum home beds once a month.
After the bugs developed resistance against many of the most powerful pesticides, such as DDT, exterminators had been increasingly relying on two chemicals—chlorfenapyr and bifenthrin. But until now, no one had looked at whether bed bugs were developing defenses against these chemicals too, says Ameya D. Gondhalekar, one of the study authors and a research assistant professor at the Center for Urban and Industrial Pest Management at the Department of Entomology at Purdue University.
While cleaning up infested areas will be helpful in controlling bedbugs, getting rid of them usually requires chemical treatments. Because treating your bed and bedroom with insecticides can be harmful, it is important to use products that can be used safely in bedrooms. Do not treat mattresses and bedding unless the label specifically says you can use them on bedding.
The main reason people seem to favor the essential oil option is that it’s considered a natural and chemical-free alternative to pesticide sprays. What they don’t realize is that today’s home pesticides are carefully regulated by the EPA to make sure that they’re safe for indoor use. The EPA also requires that health and safety guidelines are included in the product label and MSDS, to ensure that anyone who uses a spray has instructions on how to use it safely and effectively. When used correctly, even our strongest bed bug sprays won’t have any effect on you, but they will kill bed bugs more effectively than any mixture of household items like herbs or oils.
It was stated in 2012 that no truly effective insecticides were available. Insecticides that have historically been found effective include pyrethroids, dichlorvos, and malathion. Resistance to pesticides has increased significantly over time, and harm to health from their use is of concern. The carbamate insecticide propoxur is highly toxic to bed bugs, but it has potential toxicity to children exposed to it, and the US Environmental Protection Agency has been reluctant to approve it for indoor use. Boric acid, occasionally applied as a safe indoor insecticide, is not effective against bed bugs because they do not groom.
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Bed Pug Patrol doesn’t contain any harsh pesticides and can be sprayed anywhere you see signs of bed bugs. It can also be used safely on fabrics because it won’t stain them. Bed Pug Patrol also comes in various sizes and can be used as a cost-effective method for controlling large bed bug infestations. You can get more information about Bed Bug Patrol and purchase it in Amazon here.
Bedbugs may enter your home undetected through luggage, clothing, used beds and couches, and other items. Their flattened bodies make it possible for them to fit into tiny spaces, about the width of a credit card. Bedbugs do not have nests like ants or bees, but tend to live in groups in hiding places. Their initial hiding places are typically in mattresses, box springs, bed frames, and headboards where they have easy access to people to bite in the night.
But the bites will look different from person to person, and some people won’t develop any reaction whatsoever. “The same bedbug could bite two different people and one could have no reaction at all and the other can have an extreme reaction with a swollen arm or itchy rash,” says Eric Braun, a board-certified entomologist and business manager for the national pest control company Rentokil Steritech, who is based in Redding, Pennsylvania. Some people end up developing a rash that looks like eczema. (5)