Bed bug sprays usually act as an insecticide and repellent. The best kind of bed bug sprays should kill bed bugs on contact and need to be used repeatedly to help eliminate your bug problem. According to the Texas A&M University, bed bug sprays are best used in combination with other bug control methods like natural bed bug powders. This is because bed bugs don’t build up resistance to natural bug powders and products like diatomaceous earth which kills bed bugs as long as the powder is dry.5 

For more information about bed bugs, including their biology and how to recognize them, see other factsheets on the Citybugs bed bug page.  The State of Michigan has also recently published a very detailed guide to Do-it-yourself bed bug control. Also, if you decide you need professional help, check out our advice onHow to Select a Bed Bug Control Professional, ENTO-033
To ensure that all bed bugs are killed, reapply the contact and residual sprays two weeks after the initial treatment, then again two weeks after that, for a total of three applications. These reapplications make sure that any eggs that have hatched will be killed off so that they can’t create a new infestation. Bed bug powders will not need to be reapplied, as they work for as long as they remain dry and undisturbed.
Thanks to pesticide resistance, those cans of spray at your local hardware store simply will not do, Schal says, adding: "Relying strictly on chemicals is generally not a good solution." The most effective solutions are fumigation and heat treatments, but these can cost a cool $2,000 to $3,000 apiece for a single-family home. Scientists are diligently pursuing other strategies, including freezing and bait similar to that used for cockroaches. In the October 2010 issue of the Journal of Economic Entomology Schal and colleagues at the U.S. Department of Agriculture published a technique that employs inexpensive infrared and vibration sensors to track bedbug movement, which could be applied to the development of automated traps that detect the pests.

Systematically treat the room–all cracks and crevices around windows, outlets, blinds, pictures, posters and clocks on walls, baseboards, under edges of carpets and any other crevices or void areas in the room. Remember that immature bed bugs are very tiny. Dozens of bed bugs can hide in a recessed screw hole in a bed frame or dresser. Therefore it’s important that no hiding place be overlooked. Treatment can include vacuuming, but should not be limited to vacuuming only. Vacuums do not remove eggs, and will likely not remove all bed bugs from deeply infested cracks and crevices. Vacuums can remove many bed bugs from mattresses and the exterior of box springs (remember to immediately double-bag the vacuum bag after cleaning and dispose of outside in a trash can or dumpster). Sticky tape is another method of picking up bed bugs from furniture, walls, etc.
"By every metric that we use, it's getting worse and worse," says Coby Schal, an entomologist at North Carolina State University in Raleigh. Health authorities and pest control operators are regularly flooded with calls, and the epidemic may not have yet peaked. And because bedbugs are indoor pests, there are no high or low seasons throughout the year, he adds, only continual bombardment. "It's just the beginning of the problem in the U.S.," Schal says.
Low toxicity contact sprays like SteriFab™ or Bedlam® are likely to kill bed bugs only on contact. Alcohol- and soap-based sprays, are only partly effective. All of these products, once dry, are likely to provide no further control. Eggs will not be killed by alcohol-based sprays, so repeat treatments are usually needed. Be careful when using sprays containing alcohol because they may be flammable.
If you think that by discarding the whole bed means getting rid of bed bugs, you are wrong. By moving the mattress and the bed frame, you not only risk moving the bed bugs all around the house, you are also missing out on many other spots these bed bugs could be at. For example, curtains, floor panels and skirting or even the door frames are able to hide these bed bugs very well. The root causes of the infestation must be eradicated fully.
I paid $1200 for extermination heat treatment- lasted a few months and they are back- bought all new furniture! Still bugs- spray bye bye bugs spray which kills on contact but didn’t stop the infestation! This is going on 2 years now!!!! Mainly they are just in the 2 bedrooms. Ours and one that hardly no one sleeps in. But when grandkids come- they get bitten bad- I scrub, spray, vacuum & steam clean, & wash all bedding n still bit!!! Ready to burn the house down!!! HELP!!!!!! Can’t afford another $1200
It is hard to tell if you’ve been bitten by a bed bug unless you find bed bugs or signs of infestation. When bed bugs bite, they inject an anesthetic and an anticoagulant that prevents a person from realizing they are being bitten. Most people do not realize they have been bitten until bite marks appear anywhere from one to several days after the initial bite. The bite marks are similar to that of a mosquito or a flea — a slightly swollen and red area that may itch and be irritating. The bite marks may be random or appear in a straight line. Other symptoms of bed bug bites include insomnia, anxiety, and skin problems that arise from profuse scratching of the bites.
Around the time I started getting bites, I noticed more and more neighbors throwing out mattresses, furniture… I got suspicious. We live in apartments. I react differently to different kinds of bites so I can always tell the difference between mosquitoes and ants and such. I didn’t know what those bites were until I caught one of the little hellions crawling across the sheets.

Some pest control firms utilize specialized heating equipment to de-infest furnishings, rooms, and entire dwellings. The procedure involves heating up the infested item or area to temperatures lethal to bed bugs. Portable heaters and fans are used to gradually heat the air to about 120 - 130°F while monitoring with strategically placed sensors. By carefully controlling the temperature, bugs and eggs are killed wherever they may be without damaging household items. 
Bed bugs like to travel and are good hitchhikers. They will hide in suitcases, boxes and shoes to be near a food supply. They are elusive, nocturnal creatures. They can hide behind baseboards and in cracks, crevices, and folded areas of beds, bedding and adjacent furniture, especially mattresses and box springs. Bed bugs can also hide in electrical switchplates, picture frames, wallpaper and nearly anywhere inside a home, car, bus, or other shelter. Bed bugs usually come out at night for a blood meal. However, they are opportunistic insects and can take a blood meal during the day, especially in heavily-infested areas. Bed bugs usually require 5-10 minutes to engorge with blood. After feeding, they move to secluded places and hide for 5-10 days. During this time in the bed bug life cycle, they do not feed but instead digest their meal, mate, and lay eggs.
You can check bedding, mattresses, furniture, and crevices in walls for bed bug infestation. Do your inspection just before dawn, which is when they are the most active. The bugs will be larger and slower after feeding. Bedbugs will quickly flee from light, so live bugs are best located in the folds and seams of mattresses and sheets. Bedbugs are about the size of an apple seed, about 1/4 inch long. They change from light brown to purple-red after feeding. You may also see their eggs, which are about the same size as the adults. The eggs will often be in seams, cracks, or crevices.
Inspection for bed bug infestations must be very thorough. Your primary tool is a flashlight. Since bed bugs are cryptic insects and spend most of their time hiding, you will need a flashlight to find them. You must move and/or disassemble some items while searching including beds, dressers, carpets and rugs. While you inspect, be alert for a bed bug smell which has been described as an obnoxious sweetness or fresh, red raspberries. You should also look for accumulations of cast nymphal skins and for stains of blood spots on sheets and linens. A common location for bed bug infestations is a box spring. The framework is often made of wood and contains cracks can crevices suitable for harborage. Other common areas include wall voids, behind switch plates, interior corners of bedside tables, under the edges of wall to wall carpeting, couches and stuffed chairs.
Insect bites, including those from the bedbug, have been proposed as a factor contributing to the formation of a cutaneous reaction termed papular urticaria. Patients with papular urticaria have been shown to demonstrate immunoglobulin (Ig) G antibodies to bedbug (C lectularius) antigens. [10] Thus, IgG against C lectularius, Cimex pipiens, and Pulex irritans in patients with papular urticaria may contribute the pathogenesis of this condition.
Bedbugs lurk in cracks and crevices and they've been living on human blood for centuries. Though they aren't known to transmit disease or pose any serious medical risk, the stubborn parasites can leave itchy and unsightly bites. However, bedbugs don't always leave marks. The best way to tell if you have a bedbug infestation is to see the live, apple-seed-size critters for yourself. Unfortunately, once bedbugs take up residence in homes and businesses, they can be difficult to exterminate without professional help.
Bed bugs have been pestering humanity for thousands of years, but in the 1950s they finally met their match: the pesticide DDT. Then DDT was banned, but for most of the 40 years since, bed bugs have not been a major problem. Now, however, these blood-sucking vermin are back with a vengeance. That’s the bad news. The good news is that, unlike mosquitoes and ticks, bed bugs don’t spread disease, and there are practical steps you can take to prevent an infestation. And if you do get bed bugs, you can get rid of them yourself. We’ll show you what to look for, how do you get rid of bed bugs if you find them, and how to keep them out!
"In the past, bedbugs have repeatedly shown the ability to develop resistance to products overly relied upon for their control. The findings of the current study also show similar trends in regard to chlorfenapyr and bifenthrin resistance development in bedbugs," study researcher Ameya Gondhalekar, research assistant professor at Purdue's Center for Urban and Industrial Pest Management, said in the Entomology Today statement. "With these findings in mind and from an insecticide resistance management perspective, both bifenthrin and chlorfenapyr should be integrated with other methods used for bed bug elimination in order to preserve their efficacy in the long term."

Prior to World War II, bed bug infestations were common. Since the development of synthetic organic insecticides such as DDT and chlordane almost 70 years ago, bed bug infestations in buildings have declined significantly - almost disappeared. In fact, in the United States, bed bug infestations have been exceedingly rare - almost non-existent - until a few years ago.


The life cycle stages of a bed bug are egg, nymph, and adult. The reason they are called bed bugs is that they readily infest mattresses, bed frames and box springs. Eggs are laid along the edges of or around buttons on the mattresses. Eggs can also be glued to rough surfaces. Bed bug females lay about 200 eggs, usually at the rate of three or four a day. Eggs are placed in cracks, crevices and other isolated and protected shelters. Females lay eggs after a blood meal. Eggs will hatch in one or two weeks into Nymphs. Newly hatched bugs (Nymphs) begin feeding immediately. At room temperature, and with an available food supply, the nymphal period will last 14 to 30 days. They shed their skin (Instar) five times before becoming adults. Bed bugs will mate soon after becoming mature, so the time from egg hatch to egg laying is 4 to 9 weeks, under favorable conditions. The average life span of the bed bug is 6-12 months and they feed every 10 days or so during this time. Bed bugs can survive many months without a blood meal and their reproduction is high.
Waking up with bites might be the first indicator that you have a bed bug problem. Their bites are often arranged in lines or clusters on the face, neck, arms or hands. Where there are bed bugs in large numbers, you might smell a sweet, musty odor (from the bugs’ scent glands) or see rust-colored spots on your bedding or mattress caused by bed bug blood or excrement. If you look closely, you might see adult bed bugs themselves, usually in mattress folds or seams or on the wall behind the headboard. Bed bugs prefer to stay close to their food source and are typically found hiding out within 1 to 5 ft of infested beds or furniture.

It was stated in 2012 that no truly effective insecticides were available.[6] Insecticides that have historically been found effective include pyrethroids, dichlorvos, and malathion.[4] Resistance to pesticides has increased significantly over time, and harm to health from their use is of concern.[3] The carbamate insecticide propoxur is highly toxic to bed bugs, but it has potential toxicity to children exposed to it, and the US Environmental Protection Agency has been reluctant to approve it for indoor use.[33] Boric acid, occasionally applied as a safe indoor insecticide, is not effective against bed bugs[34] because they do not groom.[35]
Skin reactions from bed bug bites vary from person to person. Bites may go unnoticed or may be mistaken for flea or mosquito bites or other skin conditions. The most common skin reaction to bed bug bites are itchy red bite marks that appear clustered or in a straight line, often along the edge of clothing or where sheets were pulled up to a person's skin. Small swollen red bumps are also common. In rare cases, people may develop large, often itchy, red welts. A single bed bug bite is similar to a flea bite, except that a red area does not occur in the center. Flea bites tend to be found around the ankles while bed bugs tend to bite any exposed area of the body while a person is sleeping, such as the face, neck, arms, hands, or legs.
Dust the wall voids. Bed bugs can often travel from room to room, especially in apartments, hotels and condo's. They travel along electrical wiring and plumbing lines. Specifically treat wall voids with a hand duster either by removing wall switch plate covers and/or drill access holes discreetly between studs. Cimexa Dust or Delta Dust are excellent choices for void applications. It kills populations in walls and voids and creates a repellent, hostile environment which reduces the likelihood of bed bugs traveling through voids to other areas. Use a small hand type duster to "puff" insecticidal dusts into these areas. A light coating is all that is needed. To much dust and the bed bugs will just crawl around it.
Inspection requires knowledge, dedication and time. At minimum an inspection should involve a detailed examination of mattresses, box springs and bed frames, as well as likely hiding places for bed bugs within 20 feet of beds and other places where residents may sleep or rest, e.g., on couches). Clutter-free space will be needed to allow furnishings to be moved and manipulated for inspection. In general, rooms with more furnishings will take more time to inspect.
Isolating your bed from the rest of the house.  If you don’t use a bed, purchase a frame that gets your mattress off the floor and install bed bug interceptors under all feet of the bed frame to keep bed bugs off your bed while you are sleeping. Interceptors are special platforms or cups that are purchased to prevent bed bugs from climbing on to your bed.  An interceptor can be as simple as a sticky card placed under a bed post (sticky and messy).  Better are one of the commercial pitfall traps made specifically for this purpose.  The Climbup™ Bed bug Interceptor and BlackOut BedBug Detector (Google them) are two such products sold online. Relatively inexpensive, these cups trap bed bugs attempting to climb (or exit) the bed. If you have encased your bedding, treated your bed frame thoroughly and installed interceptors, you will be instantly protected against bed bugs.  Don’t take out your clean bedding or put it back on the bed until the bed has been treated (and dried) and encasements installed. And note that for this method to be effective, beds and bedding must not touch the floor, furniture or walls.  This would provide bed bugs other ways to climb onto the bed and foil your defenses.
Start with the bed, including mattress, box-spring and bed frame. Inspect the visible areas first. Look along all edges and corners.  Also check along all stitch lines and the mattress label. Five sides the mattress can be checked while the mattress is on the bed.  When you are finished checking the upper surfaces, you can then stand the mattress upright so you can check the bottom of the mattress.

Bag and launder (122°F/50ºC minimum) affected items. Smaller items that cannot be laundered can sometimes be de-infested by heating. Individual items, for example, can be wrapped in plastic and placed in a hot, sunny location for at least a few days (the 122°F/50ºC minimum target temperature should be monitored in the center-most location with a thermometer). Bedbugs also succumb to cold temperatures below freezing, but the chilling period must be maintained for at least two weeks. Attempts to rid an entire home or apartment of bed bugs by raising or lowering the thermostat will be entirely unsuccessful.[12]


Start in the corners and along edges of an open wall.  With the card, see if you can dig things out of the cracks and crevices. Work your way along the cracks and crevices. For example, if you are checking a baseboard along the floor, see if you can get the card between the baseboard and the floor, as well as the top of the baseboard and the wall. If you have a bare tile or wood floor, consider using a damp cloth or map to wipe the floor.  Don’t use too much water as floors can be slippery.  Look for anything moving after you wipe the floor. If you have carpeted areas vacuum the clean area. See Vacuuming Items to Capture Bed Bugs.  Don’t forget to check pictures and other items on this wall.

Bed bug bites are caused primarily by two species of the insect Cimex: Cimex lectularius (the common bed bug) and Cimex hemipterus.[3] Their size ranges between 1 and 7 mm.[7] They spread by crawling between nearby locations or by being carried within personal items.[2] Infestation is rarely due to a lack of hygiene but is more common in high-density areas.[8][2] Diagnosis involves both finding the bugs and the occurrence of compatible symptoms.[5] Bed bugs spend much of their time in dark, hidden locations like mattress seams or cracks in the wall.[2]
Bed bug females lay between 200 and 500 eggs during their lifetime in batches of three to four eggs per day. These eggs hatch after 6 to 17 days. Nymphal bed bugs molt five to six times before becoming adults. Under the best conditions, the life cycle is complete in four to five weeks, but since ideal conditions are rarely found it can take four to five months. Adult bed bugs can live 10 months or more without food. Nymphal bed bugs are known to survive for more than two months without feeding.

Begin by reducing clutter in the room; things like clothes, books, and other personal belongings shouldn’t be left on the floor, as they make treatment more difficult and add hiding places for bed bugs and eggs. Seal those items in garbage bags and store them away from the room. Any clothing that was picked up or removed from dresser drawers should be dried on high heat for at least 45 minutes. Once treated, clothing that you don’t normally wear should be stored inside garbage bags outside of the infested room.


Bed bugs are a type of insect that feed on human blood, usually at night.[7] Their bites can result in a number of health effects including skin rashes, psychological effects and allergic symptoms.[5] Bed bug bites may lead to skin changes ranging from invisible to prominent blisters.[1] Symptoms may take between minutes to days to appear.[2] Itchiness is common, while some may feel tired or have a fever.[2] Typically, uncovered areas of the body are affected and three bites occur in a row.[2] Bed bugs bites are not known to transmit any infectious disease.[5][7]
Consider using insecticides. Residual insecticides (usually pyrethroids) are applied as spot treatments to cracks and crevices where bed bugs are hiding. Increased penetration of the insecticide into cracks and crevices can be achieved if accumulated dirt and debris are first removed using a vacuum cleaner. Many readily available aerosol pesticide sprays will cause bed bugs to scatter making eradication more difficult. Dust formulations may be used to treat wall voids and attics.[16]
A number of vital tasks carried out during sleep help maintain good health and enable people to function at their best. Sleep needs vary from individual to individual and change throughout your life. The National Institutes of Health recommend about 7-9 hours of sleep each night for older, school-aged children, teens, and most average adults; 10-12 for preschool-aged children; and 16-18 hours for newborns. There are two stages of sleep; 1) REM sleep (rapid-eye movement), and 2) NREM sleep (non-rapid-eye movement). The side effects of lack of sleep or insomnia include:
Use your vacuum's nozzle attachment to capture the bed bugs and their eggs. Vacuum all seams and crevices on your mattress, bed frame, baseboards, and any other objects close to the bed or furniture in the home found to be harboring bed bugs. It is essential to vacuum daily and immediately place the vacuum's contents into a sealed plastic bag and throw it away in an outdoor garbage can.
Insecticide Application This is the most common way to get rid of bedbugs, Lazarus says. Oftentimes, the professional will use several different products to effectively treat the area, though it may take a few rounds to ensure removal. “The advantage to this method is that the residual insecticide will continue to offer protection for a period of time,” Lazarus says. “The biggest drawback is that the preparation for service is time-consuming and must be repeated prior to each service.”

To use sprays effectively to eliminate all traces of bed bugs, you need to know the signs of a bed bug infestation. The first sign that you may have bedbugs are some itchy bite marks on your skin when you wake up in the morning. Dr. Carol DerSarkissian on WebMD says that the bites from bed bugs cause red itchy bumps on the skin.3 You can learn about their other signs and symptoms in my articles on what do bed bug bites look like.
Bedbugs are small oval-shaped non-flying insects that belong to the insect family Cimicidae, which includes three species that bite people. Adult bedbugs reach 5 mm-7 mm in length, while nymphs (juveniles) are as small as 1.5 mm. Bedbugs have flat bodies and may sometimes be mistaken for ticks or small cockroaches. Bedbugs feed by sucking blood from humans or animals. Cimex lectularius is the scientific name for bedbugs.
A flashlight:  Bed bugs hide in dark areas and in cracks and crevices.  Bed bugs are a dark red to brown color, but they can be light brown if they haven’t been feeding. This makes it very hard to see them. When hunting for bed bugs hold your flashlight parallel to the surface being inspected, this will cause eggs and small bed bugs to cast a shadow, making them easier to find.
Bedbug bites may go unnoticed or be mistaken for flea or mosquito bites or other types of rash or skin conditions, since the signs of bedbug bites are difficult to distinguish from other bites or skin conditions. Bedbugs also have glands whose secretions may leave musty odors, and they also may leave dark fecal spots on bed sheets and around places where they hide (in crevices or protected areas around the bed or anywhere in the room).

Bedbugs live in any articles of furniture, clothing, or bedding, so they or their eggs may be present in used furniture or clothing. They spread by crawling and may contaminate multiple rooms in a home or even multiple dwellings in apartment buildings. They may also hide in boxes, suitcases, or other items that are moved from residence to residence or from a hotel to home. Bedbugs can live on clothing from home infestations and may be spread by a person unknowingly wearing infested clothing.

Unlike those of other insects, bed bug bites may sometimes appear in tight lines of multiple, small, red marks where multiple bed bugs have fed along an exposed area. Bed bug bites can cause itchiness. Initially, a victim may detect a slight burning sensation. The burning area then develops red bumps, known as papules or wheals (rash). In extreme cases, bites may swell dramatically or turn into blister-like skin inflammations.

Treat or isolate your bagged items. For washable items research shows that dry cleaning, washing in hot water for 30 minutes, or tumble drying for 30 minutes on high will kill all stages of bed bugs. Non-washables are a little trickier.  Items that aren’t needed for a while can just be stored. It takes 2-5 months to kill bed bugs by isolating them in bags (the warmer the temperature, the shorter the survival time for starving bed bugs). Heating bags by placing in direct sunlight is one of the most effective methods during the warm summer months.  Seven pounds of items placed in clear bags in direct sunlight on a 95 degree day will get hot enough to kill all bed bug life stages in one afternoon.  Also, placing bagged items in a chest freezer (0 degrees F) for 8-10 hours is lethal for bed bugs and their eggs. Some toys may be disinfested by cleaning with hot soapy water and/or rubbing alcohol.

Bed bugs don’t like being jostled, so they avoid hanging out in your hair or clothes, but they do like to stay close to their food source, namely you. The mattress is the first place you should inspect if you’re trying to figure out how to get rid of bed bugs fast. Bed bugs love to hang out in cracks and crevices. They can fit into any gap the thickness of a business card. One of their favorite spots is the piping along the edge of a mattress. Look for the bugs themselves, their dark droppings, your dried blood, eggs and gold-colored shells that have been left behind after molting. 

Bedbugs are highly resistant to many sprays. There are, however, certain sprays that may be able to kill bedbugs. Check with a professional exterminator about advice using sprays to try and remove the bedbugs yourself. Dead bedbugs usually won't move, may be arched back, or red in color. Ultimately, you may be better off replacing your mattress and bedding and fumigating your home to kill the bedbugs.
Some bed bug products cannot be used where others can. Also, bed bugs can build up a resistance to certain pyrethroids, making them difficult to treat. This is why using a variety of products to kill and control bed bugs will produce the best results. We recommend using one of our bed bug kits. These kits include our most powerful and effective products for a variety of applications to save you time and money.
DIY heat treatments most often just drive bed bugs deep into wall voids and hard-to-reach spaces in a structure. When the heat is turned off, the bugs return to living and sleeping areas. It has no impact at all. But, in worst case scenarios, where desperate people have gone to greater lengths to destroy these tormenting pests, it has resulted in damage to belongings, the death of pets, structural fires, and in tragic cases, a loss of human life.
Bed bugs are tiny, flat, wingless insects that range in color from nearly white to deep brown/reddish. The parasitic pests get their name from their hiding spot of choice – they prefer burrowing into bed frames and mattresses during the day, then become active at night when they feed on people and pets. Bed bugs are resilient pests that can hitch a ride on luggage, furniture, storage boxes, backpacks and clothing (but rarely humans), very quickly causing an infestation.

DIY heat treatments most often just drive bed bugs deep into wall voids and hard-to-reach spaces in a structure. When the heat is turned off, the bugs return to living and sleeping areas. It has no impact at all. But, in worst case scenarios, where desperate people have gone to greater lengths to destroy these tormenting pests, it has resulted in damage to belongings, the death of pets, structural fires, and in tragic cases, a loss of human life.
Prepare the room by separating treated from untreated furniture.  This will involve moving all your furniture to one side of the infested room (Remember, you’ve already assessed which rooms you think are infested.  You may not need to do this in every room).  The process is important because if you treat half of the items in a room and leave other areas untreated, bed bugs may return to the previously treated areas from untreated sites. Take all clothes from drawers, infested closets, etc. and double bag them in clear plastic bags (clear bags are easier to see where things are). Also double bag all personal items (toys, papers, books, electronics, CDs, or anything that could serve as a hiding place for bed bugs) and set them aside until they can be carefully treated, cleaned or inspected. 
To ensure that all bed bugs are killed, reapply the contact and residual sprays two weeks after the initial treatment, then again two weeks after that, for a total of three applications. These reapplications make sure that any eggs that have hatched will be killed off so that they can’t create a new infestation. Bed bug powders will not need to be reapplied, as they work for as long as they remain dry and undisturbed.
It should also be noted that pest management professionals are subject to state regulation, licensing and regulation, while bed bug dog teams are typically unregulated. In Illinois, for example, bed bug detection dogs are regarded as inspection tools, not devices that facilitate the application of pesticides. A few private organizations certify dogs and their handlers as bed bug detectors, holding them to certain standards before awarding certification. But at present, these organizations, like dogs and handlers, are not subject to regulations that govern those who apply pesticides to control bed bugs. Nevertheless, the National Pest Management Association (NPMA) recommends that bed bug detection teams be independently certified and adhere to the minimum standards found in the NPMA’s Best Management Practices for Bed Bugs (see RESOURCES for more info). 
What’s the best way to get rid of bed bugs? Stop feeding them. To prevent those unwanted dinner guests, isolate your mattress from the rest of the room. Start by pulling the bed away from the wall and away from other furniture like nightstands and chairs. Remove box spring skirting that hangs down to the floor. Oversize blankets that drape to the floor can also act as a ladder for the little buggers.

Symptoms may not appear until some days after the bites have occurred.[5] Reactions often become more brisk after multiple bites due to possible sensitization to the salivary proteins of the bed bug.[3] The skin reaction usually occurs in the area of the bite which is most commonly the arms, shoulders and legs as they are more frequently exposed at night.[5] Numerous bites may lead to an erythematous rash or urticaria.[5]
Bed bug sprays usually act as an insecticide and repellent. The best kind of bed bug sprays should kill bed bugs on contact and need to be used repeatedly to help eliminate your bug problem. According to the Texas A&M University, bed bug sprays are best used in combination with other bug control methods like natural bed bug powders. This is because bed bugs don’t build up resistance to natural bug powders and products like diatomaceous earth which kills bed bugs as long as the powder is dry.5
Bed bugs occur in all regions of the globe.[7] Rates of infestations are relatively common, following an increase since the 1990s.[3][4][6] The exact causes of this increase is unclear; with proposals including greater travel, more frequent exchange of second-hand furnishings, a greater focus on control of other pests, and increasing resistance to pesticides.[4] Bed bugs have been known human parasites for thousands of years.[2]
Units that produce “dry” steam are less likely to damage household goods. Steam must be at least 113 degrees Fahrenheit (F), the minimum temperature to kill bed bugs, and care must be taken to reduce pressure so that bed bugs are not literally “blown away” before they can be killed by the steam. Steaming should be avoided around hazards such as electrical outlets.
A number of vital tasks carried out during sleep help maintain good health and enable people to function at their best. Sleep needs vary from individual to individual and change throughout your life. The National Institutes of Health recommend about 7-9 hours of sleep each night for older, school-aged children, teens, and most average adults; 10-12 for preschool-aged children; and 16-18 hours for newborns. There are two stages of sleep; 1) REM sleep (rapid-eye movement), and 2) NREM sleep (non-rapid-eye movement). The side effects of lack of sleep or insomnia include:

While most of the bed bugs were wiped out by the chemicals, three groups continued to thrive after being treated with chlorfenapyr, and five groups were still kicking after being treated with bifenthrin. That means that while some bed bugs will respond to these chemicals, others won't—and it's likely that more and more bugs will become resistant over time.
If you think that by discarding the whole bed means getting rid of bed bugs, you are wrong. By moving the mattress and the bed frame, you not only risk moving the bed bugs all around the house, you are also missing out on many other spots these bed bugs could be at. For example, curtains, floor panels and skirting or even the door frames are able to hide these bed bugs very well. The root causes of the infestation must be eradicated fully.
When bed bugs are suspected, sleeping and resting places should be thoroughly inspected. Check all possible hiding places, mindful that bed bugs, especially the young nymphs and eggs, can fit into very tiny cracks and crevices. Don’t overlook places where pets rest, and where bats or birds have entered structures. In these instances, bat or bird bugs, not bed bugs, may be present. If bats or birds are a source of infestation, they should be excluded from the premises. Note that bats and most bird species are protected by law and should not be killed. Contact the Illinois Department of Natural Resources for guidelines on bat or bird exclusion and removal.
Probably chiggers -- they are very small, red mites that usually cannot be seen with the naked eye. They are about as small as the period at the end of this sentence. To stop the itching, use OraJel (usually sold for teething babies), which contains benzocaine (an anesthetic). Also, rub in hydrocortisone cream. To prevent chigger bites, wear long pants and stuff the cuffs into your socks.
What’s the best way to get rid of bed bugs? Stop feeding them. To prevent those unwanted dinner guests, isolate your mattress from the rest of the room. Start by pulling the bed away from the wall and away from other furniture like nightstands and chairs. Remove box spring skirting that hangs down to the floor. Oversize blankets that drape to the floor can also act as a ladder for the little buggers.

Buy “say bye bugs” I think its liquid diatemacious earth food grade, I put powder down on my couch took all loose wood off and they were hidden under material sprayed and dusted it with the diatemacious earth kills them on contact, of course you have to do it 10 days. Because even dead they can lay eggs……keep spraying every day, wash bedding in hot water dry at least 45 min on high heat, after you think they are dead, put mattress or furniture in bed bug bag for a year, because they can stay alive for a year without eating…om working on it going on 3 days now!!
Check the mattress throughly, paying close attention to seams and tufts along the edges. Flip the mattress over and inspect the bottom carefully as well. Pay particular attention to any rips in the fabric. View the fabric on the bottom of the box spring and shine a flash light to verify that bed bugs have not penetrated the interior of the box spring.
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