Bed bugs have a fast and large reproduction nature. On an average, they can reproduce within 200 to 250 eggs at one time, and hatch during an interval between 6 to 10 days. Bed bugs largely live between 4 months to 6 months, and a 1-time treatment is not sufficient to cover the Bed Bug life stages. A 3 times treatment integrated with steam treatment and follow ups across 1.5 to 2 months is usually recommended. Read more here on 6 Questions to Get the Best Treatment for Bed Bugs.
To treat an allergic reaction, the doctor may prescribe an antihistamine, corticosteroid, or epinephrine injection. If the area is infected, he or she might prescribe an antibiotic or recommend an over-the-counter antiseptic. Finally, if it’s severe itchiness that you’re dealing with, applying corticosteroid or taking an antihistamine in pill or liquid form may be able to help.
Mix 3 oz per gallon or 0.75 oz per quart and spray with a low pressure sprayer into the areas where the bed bugs are hiding. Typical areas include bed frames, headboards, under beds, baseboards, moldings, behind pictures,etc. Remember to apply in the joints and crevices of furniture. If the crack and crevice is too small, use an aerosol with a crack and crevice tip (recommendations are below.)
One method of applying freezing temperatures to bed bugs entails the use of carbon dioxide (CO2) applied as “snow” with a portable application device, i.e., Cryonite™. When applied directly onto bed bugs, the frozen CO2 will kill them. However, this method is similar to using contact pesticides, that is, there is no residual activity. It can kill only as many bed bugs as the applicator can find. The advantage of using this type of freezing device is that bed bugs may be killed quickly and without the use of more hazardous pesticides. Again, this is not a stand-alone treatment, and it is recommended that it be used as a supplemental to the application of residual pesticides and/or other means of control.
Bedbugs may enter your home undetected through luggage, clothing, used beds and couches, and other items. Their flattened bodies make it possible for them to fit into tiny spaces, about the width of a credit card. Bedbugs do not have nests like ants or bees, but tend to live in groups in hiding places. Their initial hiding places are typically in mattresses, box springs, bed frames, and headboards where they have easy access to people to bite in the night.
One method of applying freezing temperatures to bed bugs entails the use of carbon dioxide (CO2) applied as “snow” with a portable application device, i.e., Cryonite™. When applied directly onto bed bugs, the frozen CO2 will kill them. However, this method is similar to using contact pesticides, that is, there is no residual activity. It can kill only as many bed bugs as the applicator can find. The advantage of using this type of freezing device is that bed bugs may be killed quickly and without the use of more hazardous pesticides. Again, this is not a stand-alone treatment, and it is recommended that it be used as a supplemental to the application of residual pesticides and/or other means of control.
My husband works for a garbage company (this is how we think the invasion started) and at the moment they are localized to our bedroom and our bathroom. However, the first place we found them was in our headboard & footboard. It is wood with an intricate carving. We checked the mattress and box spring and didn’t find a thing. But they LOVE that wood.
Use precautions in your own home. Keep the plastic covering that comes on your mattress when purchased new. Purchase special bedbug covers for you mattress and box spring. Make sure that they are quality ones with heavy duty zippers and constructed with special fabric that doesn't rip easily. Don't buy the cheap versions which are not thick enough to prevent the bedbugs from sticking their feeding tubes into the skin through the cover.[19]
If you need to treat items that can’t be laundered or steamed, you can use a portable bed bug heater, like a ZappBug Oven or a ThermalStrike Ranger. These heaters can safely treat household items like books, papers, CDs, and dry clean only clothing. Not only are bed bug heaters an effective part of a bed bug treatment process, but they’re one of the most popular prevention tools on the market. When you come home from a trip, just put your suitcase in the heater, zip it shut, and turn it on. In just a few hours, any bed bugs or eggs hiding in your belongings will be dead.
The scientific name for bed bugs is Cimex lectularius. They are small creatures that grow up to 5 mm in size, or about the size of an apple seed. They have a flat oval-shaped body and will become significantly larger if they have fed. According to the United States Environmental Protection Agency, bed bugs start life as a tiny egg, then grow into a nymph before becoming an adult.1

Bedbugs bite and suck blood from humans. Bedbugs are most active at night and bite any exposed areas of skin while an individual is sleeping. The face, neck, hands, and arms are common sites for bedbug bites. The bite itself is painless and is not noticed. Small, flat, or raised bumps on the skin are the most common sign; redness, swelling, and itching commonly occur. If scratched, the bite areas can become infected. A peculiarity of bedbug bites is the tendency to find several bites lined up in a row. Infectious-disease specialists refer to this series of bites as the "breakfast, lunch, and dinner" sign, signifying the sequential feeding that occurs from site to site. In some people, the bites can take several days to develop. The signs may become apparent up to 14 days after the bite has occurred.
Scrub infested surfaces with a stiff brush to dislodge eggs. Vacuum the room extensively. Use a vacuum hose attachment to thoroughly vacuum cracks and crevices on furniture and along baseboards on the walls. Vacuum along baseboards, furniture, bed stands, rails, headboards, foot boards, bed seams, tufts, buttons, edges of the bedding, as well as the edges of the carpets (particularly along the tack strips). A good vacuum cleaning job may remove particles from cracks and crevices to encourage greater insecticide penetration. Bed bugs cling tightly to surfaces, so it is best to vacuum by scraping the end of the vacuum attachment over the infested areas to pull out the bed bugs. Caution: It is not good to use a bristle attachment, because you may transfer bed bugs to other areas since they cling to the brush. Dispose of vacuum cleaner bags after you are finished in an outdoor trashcan.
The likelihood of bed bugs increases if the affected individual has been traveling, or if they have acquired used beds or furnishings before symptoms started to appear. Bed bugs also are suspect if you wake up with itchy welts you did not have when you went to sleep. It’s important to recognize, however, that not all bite-like reactions are due to bed bugs. Confirmation requires finding and identifying the bed bugs, shed skins, fecal spots, etc., which often requires the help of a professional. (Other possible sources of irritation that may be mistaken for bed bugs are discussed in University of Kentucky entomology fact sheet ENT-58, Invisible Itches: Insect and Non-Insect Causes). 
Bed bugs have a fast and large reproduction nature. On an average, they can reproduce within 200 to 250 eggs at one time, and hatch during an interval between 6 to 10 days. Bed bugs largely live between 4 months to 6 months, and a 1-time treatment is not sufficient to cover the Bed Bug life stages. A 3 times treatment integrated with steam treatment and follow ups across 1.5 to 2 months is usually recommended. Read more here on 6 Questions to Get the Best Treatment for Bed Bugs.
Some preparation is still required (e.g. removal of heat-sensitive items such as aerosol cans, indoor plants and medications), but it is seldom necessary to bag, launder and/or hot dry bedding and clothing since these items will be heated along with other furnishings. Another advantage of heat treatment is that infestations can often be eliminated in one day, rather than over multiple days or weeks. Conversely, heat treatment alone has no lasting (residual) effect should bed bugs be reintroduced into the dwelling. Consequently, some companies recommend concurrently applying residual insecticides. To further minimize reintroduction, occupants are advised to take as few belongings as possible with them while the heat treatment is in progress.    
If you need to treat items that can’t be laundered or steamed, you can use a portable bed bug heater, like a ZappBug Oven or a ThermalStrike Ranger. These heaters can safely treat household items like books, papers, CDs, and dry clean only clothing. Not only are bed bug heaters an effective part of a bed bug treatment process, but they’re one of the most popular prevention tools on the market. When you come home from a trip, just put your suitcase in the heater, zip it shut, and turn it on. In just a few hours, any bed bugs or eggs hiding in your belongings will be dead.
If all other options have been exhausted, you may need to seek a professional PMP (Pest Management Professional). There are pesticides that are approved for professionals to use during a infestation. These pesticides, however, are not always effective, and typically not as effective as steam cleaning, excessive heat, or excessive cold. The exterminator may opt to treat the area with carbon dioxide.
Nightstands and dressers may need to be emptied and examined inside and out, and tipped over to inspect the woodwork underneath. Oftentimes the bugs will be hiding in cracks, corners, and recesses. Other common bed bug hiding places include: along and under the edge of wall-to-wall carpeting, especially behind beds and sofas; cracks in wood molding; ceiling-wall junctures; behind wall-mounted pictures, mirrors, outlets and switch plates; under loose wallpaper; clothing and clutter within closets; and inside clocks, phones, televisions and smoke detectors.
The mechanism of skin injury by arthropods depends on the structure of the mouthparts. These insects are categorized as vessel feeders if they insert the tip into a capillary or as pool feeders if they feed on the extravasated blood from damaged tissue. They often inject different pharmacologically active substances (eg, hyaluronidase, proteases, kinins), which may cause different skin reactions (eg, erythema, wheal, vesicle, hemorrhagic nodule). See the following images.
^ Kambu, Kabangu; Di Phanzu, N.; Coune, Claude; Wauters, Jean-Noël; Angenot, Luc (1982). "Contribution à l'étude des propriétés insecticides et chimiques d'Eucalyptus saligna du Zaïre (Contribution to the study of insecticide and chemical properties of Eucalyptus saligna from Zaire ( Congo))". Plantes Médicinales et Phytothérapie. 16 (1): 34–38. hdl:2268/14438.
While the mattress and box spring are left to dry, spray down the joints of the bed frame, headboard, and footboard with a contact spray and residual spray. The contact spray will kill bed bugs quickly and then evaporate, while the residual spray will kill bed bugs over several weeks. Remember to follow the sprays’ product labels and MSDS for safe and effective usage.
Apply as a coarse, low-pressure spray to harborage areas including crevices, baseboards, loose plaster, behind bed frames and headboards, beneath beds and furniture, and to bedsprings and bed frames. After removal of bed linens, apply Transport Mikron to mattress and boxsprings. Apply to tufts, edges, seams and folds (do not spray clothes or bed linens). Your may apply it to furniture, but not to areas where there is direct access to seating or arm placements. Infested bed linens should not be treated, but should be removed, placed in sealed plastic bags, and taken for laundering and drying at high temperatures.
Bed bug bites are caused primarily by two species of the insect Cimex: Cimex lectularius (the common bed bug) and Cimex hemipterus.[3] Their size ranges between 1 and 7 mm.[7] They spread by crawling between nearby locations or by being carried within personal items.[2] Infestation is rarely due to a lack of hygiene but is more common in high-density areas.[8][2] Diagnosis involves both finding the bugs and the occurrence of compatible symptoms.[5] Bed bugs spend much of their time in dark, hidden locations like mattress seams or cracks in the wall.[2]
Low toxicity contact sprays like SteriFab™ or Bedlam® are likely to kill bed bugs only on contact. Alcohol- and soap-based sprays, are only partly effective. All of these products, once dry, are likely to provide no further control. Eggs will not be killed by alcohol-based sprays, so repeat treatments are usually needed. Be careful when using sprays containing alcohol because they may be flammable.
Bedbug infestations seem to be increasing around the world at an alarming rate, possibly due to insecticide resistance. [1] Resistance to pyrethroid insecticides is already widespread in the United States. The bedbug occurs in aggregations when conditions are favorable, but the arthropods disperse when conditions are unfavorable. [2] Active female dispersal can potentially lead to treatment failures and should be taken into account when using control methods.
Bed bugs were mentioned in ancient Greece as early as 400 BC, and were later mentioned by Aristotle. Pliny's Natural History, first published circa AD 77 in Rome, claimed bed bugs had medicinal value in treating ailments such as snake bites and ear infections. (Belief in the medicinal use of bed bugs persisted until at least the 18th century, when Guettard recommended their use in the treatment of hysteria.[51])
Bed bugs love fast food. They like to feed and then scurry back to their hiding places. They try to avoid crawling all over their food for fear of waking it/us. They usually bite the bare skin they find closest to the mattress. That’s why it’s common to see two or three bite marks in a line along the skin that was in contact with the mattress or pillow. When this happens it’s time to learn how to get rid of bug beds fast.
When the controversial pesticide DDT was banned in 1972, most bed bugs were already resistant to it, Schal says, and today's populations are even more widely resistant thanks to the use of a new class of pesticides. Pyrethroids, the main class of pesticides used against bedbugs today, targets sodium channels in bedbug cells, just like DDT. Consequently, as bedbugs develop resistance to pyrethroids, they also become cross-resistant to DDT.
"By every metric that we use, it's getting worse and worse," says Coby Schal, an entomologist at North Carolina State University in Raleigh. Health authorities and pest control operators are regularly flooded with calls, and the epidemic may not have yet peaked. And because bedbugs are indoor pests, there are no high or low seasons throughout the year, he adds, only continual bombardment. "It's just the beginning of the problem in the U.S.," Schal says.
After treating a mattress or box spring for bed bugs, we recommend encasing each in a bed bug proof cover. This will prevent re-infestation and will make future inspections and treatments easier. Be sure any product that has been sprayed or applied to your mattress is dry before you cover the mattress with a bed bug proof cover. You can make the bed with your freshly laundered linens over a bed bug proof mattress cover.
Bed bugs will also succumb to cold temperatures below 32°F, but the freezing temperatures must be maintained for a longer period (e.g., one to two weeks). Consequently, heating tends to be a better option throughout much of the country. Efforts to rid entire dwellings of bed bugs by raising or lowering the thermostat will be unsuccessful, although pest control firms are able to achieve lethal temperatures with supplemental heaters (see the subsequent section entitled "Heat Treatments" for more details). 

People don't often consider bed bugs until they've left their mark. The appearance of flat, red welts in zigzag lines or small clusters is a key sign of bed bugs on humans. Bed bugs can also leave their bites in straight rows and, while they don't spread diseases to humans, their bites are quite irritating and scratching them can lead to bleeding and infection.
Bed bugs are very hardy insects. Both adults and nymphs can survive prolonged periods without food or under adverse temperature conditions. Adults can live for a year or longer without feeding and can survive over winter in an unheated building. Nymphs are not as hardy as adults, but they can survive for considerable periods under adverse conditions.
That means despite your preventive steps, bed bugs could still get into your house. But of course, that doesn’t translate that taking preventive measures is futile. In contrast, it is a great help in reducing the chance of bed bugs to infest. Nonetheless, it couldn’t completely protect you and your home from the said pests. Hence, you must always be ready to kill bed bugs whenever they get past your defenses.

Today, bedbugs can be found in every State in the United States, and almost every city. Bedbugs are so common now that the federal government considers them almost "epidemic". The National Pest Management Association has declared war on bed bugs and has held bedbug meetings all across the Nation to help educate pest control companies in an effort to help control them.
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