Bed bug sprays usually act as an insecticide and repellent. The best kind of bed bug sprays should kill bed bugs on contact and need to be used repeatedly to help eliminate your bug problem. According to the Texas A&M University, bed bug sprays are best used in combination with other bug control methods like natural bed bug powders. This is because bed bugs don’t build up resistance to natural bug powders and products like diatomaceous earth which kills bed bugs as long as the powder is dry.5 

Monitor your home. Bed bugs like to hide in cracks and crevices like walls, luggage, boxes, and clothing, but since they feed on humans while they sleep, they’re most commonly found in beds. If you suspect an infestation, or if you live in an apartment building with a bed bug problem, regularly inspect your bed sheets, mattress (including underneath), and box-spring seams for bugs. They’re flat and oval-shaped, with red or brown bodies, roughly the size of an apple seed. Watch for adults, nymphs, and eggs, as well as exoskeletons (casings that the bugs leave behind when they molt) and dark, rust-colored spots (feces).
The size of bed bug bites varies with a number of different factors. Bed bugs inject an anti-coagulant along with their saliva when they pierce the skin to take a blood meal. This anti-coagulant is mostly responsible for how a person reacts to the bite and determines the size of the bug’s bite. Since people will have various sensitivities to the bed bug’s bite, the size of the bite will vary, as well. Another factor that influences the size of a bed bug reaction is the number of times a person is bitten. Bite reactions of people bitten many times are also variable, and their response may be either more or less intense as the number of bites increases.
Preparing for bed bug treatment is tedious yet important. Very comprehensive preparation is necessary when infestations are heavy and the bugs are widely dispersed. More limited prep may be adequate for light infestations since at these levels the bed bugs typically are more confined to sleeping areas (beds, sofas, and recliners). Pest control firms have their own policies, however, regarding preparation requirements which may also depend on the manner of treatment. 

Bedbug bites can lead to anxiety, sleeplessness and even secondary infections, but there have been no reported cases of bedbugs transmitting disease to humans. They do, however, harbor human pathogens: At least 27 viruses, bacteria, protozoa and more have been found in bedbugs, although these microbes do not reproduce or multiply within the insects. Canadian researchers announced (pdf) in the June issue of Emerging Infectious Diseases that bedbugs isolated from three individuals in a Vancouver hospital carried methicillin-resistant Staphylococcus aureus, aka MRSA. Still, there have been no reported cases that the bugs actually transmit human disease.

If the bed bugs are coming from someplace other than your bed, I’d sprinkle uncalcinated diatomaceous earth around cluttered areas and the walls, and bleach the crap out of surrounding furniture. What the diatomaceous earth does is basically attach to their exoskeleton, dehydrate the insect, and they’ll either die of dehydration or get shredded apart as they crawl. Unless your pet or kid would directly eat the diatomaceous earth, it is safe to be in contact with since it’s not a chemical pesticide and it’s fairly cheap.

First off you should ALWAYS go to pest control if you think you have bedbugs! You shouldn’t try and get rid of them yourself, 99% of the time it does not work. Plus even if you removed infected areas and wash them it wouldn’t kill the eggs. Plus bedbugs are very easy to get but very hard to get rid of. So you should never do it yourself it won’t work!

Vinegar can kill bed bugs if it comes into direct contact with them and it may help repel them from areas where it is sprayed. However, vinegar cannot be your only defense against bedbugs. For one, vinegar only works if you can see the bugs, and often they will hide or even just be too small to see easily. Second, vinegar will not kill bedbug eggs, which means that vinegar alone will never stop an infestation. Vinegar also needs to be reapplied frequently to have any effectiveness.

Bed bug bites: What you need to know Bed bugs are small, parasitic insects that feed on human blood. They often bite humans during the night or early morning when people are asleep. While they don't carry disease, they can cause irritation, sores, and itchiness that might prevent a good night's sleep. Learn how to identify, control, and prevent bed bugs. Read now