Prepare the room by separating treated from untreated furniture.  This will involve moving all your furniture to one side of the infested room (Remember, you’ve already assessed which rooms you think are infested.  You may not need to do this in every room).  The process is important because if you treat half of the items in a room and leave other areas untreated, bed bugs may return to the previously treated areas from untreated sites. Take all clothes from drawers, infested closets, etc. and double bag them in clear plastic bags (clear bags are easier to see where things are). Also double bag all personal items (toys, papers, books, electronics, CDs, or anything that could serve as a hiding place for bed bugs) and set them aside until they can be carefully treated, cleaned or inspected. 
 Adult bed bugs are about 3/16” long and reddish-brown, with oval-shaped, flattened bodies. They are sometimes mistaken for ticks, cockroaches, carpet beetles or other household insects. The immature bed bugs (nymphs) resemble the adults, but are smaller and lighter in color. Bed bugs do not fly, and they don’t jump like fleas do ― but they can crawl rapidly over floors, walls, ceilings and other surfaces. Adult females lay their eggs in secluded places, depositing 1, 2 or more eggs per day, potentially hundreds during their lifetime. The eggs are tiny (about the size of a dust spec), whitish and hard to see without magnification, especially on light-colored surfaces. When first laid, the eggs are sticky, causing them to adhere to surfaces. At room temperatures, bed bug eggs hatch in about a week. Newly emerged nymphs are straw-colored and no bigger than a pinhead.
"In the past, bedbugs have repeatedly shown the ability to develop resistance to products overly relied upon for their control. The findings of the current study also show similar trends in regard to chlorfenapyr and bifenthrin resistance development in bedbugs," study researcher Ameya Gondhalekar, research assistant professor at Purdue's Center for Urban and Industrial Pest Management, said in the Entomology Today statement. "With these findings in mind and from an insecticide resistance management perspective, both bifenthrin and chlorfenapyr should be integrated with other methods used for bed bug elimination in order to preserve their efficacy in the long term."
Some pest control firms also employ commercial steamers or spot-freezing equipment to treat areas where bed bugs are found or suspected. Used correctly, they kill bugs and eggs on contact. Neither method, however, affords residual protection against bed bugs which may have been missed. Steaming and spot-freezing equipment also have limited ability to penetrate fabric, wood, and other materials where bed bugs often reside. 

Bring in only what is needed, and avoid sitting or placing coats and other items on beds, floors and sofas where the bugs commonly reside. Essential items can be placed on a tabletop or other hard surface, preferably away from bedrooms and sleeping areas. Better to sit on a hard (non-upholstered) chair than on sofas and recliners. Also try to avoid leaning or brushing against beds and upholstered furniture. If such items are carried out of infested dwellings (e.g., by sanitation workers or firefighters), it’s best to wrap them in plastic or at least not hold them against your body during transport. Emergency Medical (EMS) personnel may need to take additional precautions, such as removing a patient’s bed bug-infested shoes or clothing, or installing plastic sheeting before transporting them in the emergency vehicle.    
Because their bodies are flat, they can hide under the smallest spots like the border of beds, under the mattress, edges of carpets, couches, cracks in the walls and ceilings, in your pillows, under your bed sheets, behind electrical plugs and wall sockets, in your cupboards and dressers, or under furniture. In fact, bed bugs prefer any fabric materials. They can travel pretty good distances, too. Expect them to be able to be found anywhere in the room.
A number of other symptoms may occur from either the bite of the bed bugs or from their exposure. Anaphylaxis from the injection of serum and other nonspecific proteins has been rarely documented.[5][10] Due to each bite taking a tiny amount of blood, chronic or severe infestation may lead to anemia.[5] Bacterial skin infection may occur due to skin break down from scratching.[5][11] Systemic poisoning may occur if the bites are numerous.[12] Exposure to bed bugs may trigger an asthma attack via the effects of airborne allergens although evidence of this association is limited.[5] There is no evidence that bed bugs transmit infectious diseases[5][7] even though they appear physically capable of carrying pathogens and this possibility has been investigated.[5][3] The bite itself may be painful thus resulting in poor sleep and worse work performance.[5]
Waking up with bites might be the first indicator that you have a bed bug problem. Their bites are often arranged in lines or clusters on the face, neck, arms or hands. Where there are bed bugs in large numbers, you might smell a sweet, musty odor (from the bugs’ scent glands) or see rust-colored spots on your bedding or mattress caused by bed bug blood or excrement. If you look closely, you might see adult bed bugs themselves, usually in mattress folds or seams or on the wall behind the headboard. Bed bugs prefer to stay close to their food source and are typically found hiding out within 1 to 5 ft of infested beds or furniture.
Bed bug females lay between 200 and 500 eggs during their lifetime in batches of three to four eggs per day. These eggs hatch after 6 to 17 days. Nymphal bed bugs molt five to six times before becoming adults. Under the best conditions, the life cycle is complete in four to five weeks, but since ideal conditions are rarely found it can take four to five months. Adult bed bugs can live 10 months or more without food. Nymphal bed bugs are known to survive for more than two months without feeding.
Bed bug females lay between 200 and 500 eggs during their lifetime in batches of three to four eggs per day. These eggs hatch after 6 to 17 days. Nymphal bed bugs molt five to six times before becoming adults. Under the best conditions, the life cycle is complete in four to five weeks, but since ideal conditions are rarely found it can take four to five months. Adult bed bugs can live 10 months or more without food. Nymphal bed bugs are known to survive for more than two months without feeding.
You can make a natural bed bug bite treatment by putting 1 cup distilled water in a spray bottle and adding 10-15 drops tea tree oil. Shake well and spray on areas of skin that have clusters of bed bug bites. Or, you could spray the remedy on a cotton pad and apply to the itchy bumps on your skin. You can also dilutes tea tree oil with a carrier oil, such as coconut oil or sweet almond oil (a few drops of tea tree per one tablespoon of carrier oil).
Now that you’ve killed the bed bugs hiding in your bed, it’s time to put up defensive measures to keep them out. Remember, bed bugs can be hiding in all sorts of cracks and crevices throughout your bedroom – in furniture, along baseboards, and inside of the walls – so you need a way to keep them out of your freshly treated bed. By cutting off the infestation’s food supply (you), you halt their breeding and reproductive cycle, making the treatment a whole lot easier.
New tactics may be needed for this escalating public health concern in locations with high occupant turnover, such as hotels, hospitals, and nursing homes. [3] Indeed, in the past decade bedbugs have become a worldwide urban pest, with the number of American households affected markedly increased. [4] Genetic data suggest that C lectularius may be undergoing lineage divergence through host association. [5]
Pesticides alone are not the answer to bed bugs. Most of the commonly used pesticides today, including professional products and consumer products advertised for control of bed bugs, are at best moderately effective at controlling these pests. Pesticides must be used with care for safety and with attention to proper application to work well. Aerosol “bug bombs” or “fumigators” are also mostly ineffective in eliminating bed bugs. Aerosol insecticides mainly kill insects that are exposed, and out of their hiding places, not those hidden behind baseboards, in cracks and crevices of the bed, under carpet edging and in walls.
I can definitely understand. This is has been going on with us for almost a year. My hands and arms look like I have leprocy or something. Horrible blisters, rash, scabs, and bunches of “bumps” especially in my right hand. I wind up with painful blood blisters some times. I am living on benedryl and calamine lotion. I hate going out because of what I look like. I have taken to using cover up and foundation on my hands to make the mess less noticable. i have a long-sleeved summer weight sweater that I wear whenever I do have to go out.
It's becoming easier to find bed bug mattress covers in local hardware stores. Menard's has one for 24.99 for all sizes. There are others, but beware! Some low quality versions are only plastic, tear easily, and have horrible cheap zippers. The real ones are made of a special fabric and heavy duty zippers. Also when you buy a new mattress, keep the plastic on as well as using a bug cover.
When professionals need to treat an infestation, they don’t reach for rubbing alcohol or cedar oil or a blow dryer. They use a proven treatment process that involves a combination of proven products to get the job done. It’s not about whether or not a certain item can kill bed bugs, it’s about whether that item is the ideal part of a treatment that will actually get rid of an infestation. After all, your shoe would have a 100% kill rate on any bed bugs you smack with it – that doesn’t mean you can expect to be bed bug free after a diligent afternoon of shoe-wielding.
You should look for traces of the insects in the folds of your mattresses, box springs and other places where they are likely to hide. You might be able to find their papery skins, which get cast off after molting and look like popcorn kernels but are smaller and thinner, Harlan said. They also leave small, dark-colored spots from the blood-filled droppings they deposit on mattresses and furniture. If you can touch the spot with a water-soaked towel and it runs a rusty, reddish color, you're probably looking at a fresh drop of bedbug feces, Harlan said.
While vacuuming may seem like an obvious remedy, it is fairly unconventional in the sense that it does not usually prove effective against the majority of the bed bugs in a contained area. Due to its low level of effectiveness, it is generally not recommended as a sole treatment. Vacuuming can, however, increase the effectiveness of other treatments.
If you arrive home and discover that you have brought some unwanted guests home with you, immediately notify the hotel of your discovery. Having a possible infestation in hotels and motels can be a public relations nightmare for the owners. Politely ask them to pay for any and all costs incurred to rid your clothing and home of a possible new infestation.
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